ESCRS - PPE1.03 - Interdevice Agreement Of Corneal Measurements Using Four Imaging Systems

Interdevice Agreement Of Corneal Measurements Using Four Imaging Systems

Published 2026 - 44th Congress of the ESCRS

Reference: PPE1.03 | Type: ESONT Abstract | DOI: 10.82333/9932-4j69

Authors: Mrs Stella Georgiadou 1 , A/Prof. Athina Plakitsi* 2 , A/Prof. Evangelos Pateras 2 , Dr Constantinos Karabatsas 3

1Optics and Optometry,University of West Attica,Athens,Greece;LaserVision Ambulatory Eye Surgery Unit,Athens,Greece, 2Optics and Optometry,University of West Attica,Athens,Greece, 3Optics and Optometry,University of West Attica,Athens,Greece;LaserVision Ambulatory Eye Surgery Unit,Athens,Greece;Attiko Eye Center,Athens,Greece

Purpose

To compare corneal power, keratometry, pachymetry, astigmatism and corneal irregularity indices obtained from four anterior segment imaging devices and to assess their agreement and interchangeability.

Setting

University based ophthalmic research center and ambulatory eye care clinics in Greece.

Methods

In this prospective cross sectional study, 206 eyes of 103 healthy subjects were examined using Pentacam HR (Oculus,  Wetzlar, Germany), RTVue 100 AS - OCT(Optovue, Fremont, CA, USA), Cassini ((i-Optics) and VARIO Topolyzer (Alcon Laboratories, Worth, Texas) . Equivalent keratometry, net or total corneal power, pachymetry, astigmatism and corneal irregularity indices were analyzed. Normality testing, paired parametric or non parametric tests with Bonferroni correction, and correlation analysis were performed.

Results

Strong correlations were observed among devices for most keratometric and pachymetric parameters (r up to 0.99, p<0.001). However, statistically significant inter device differences were detected for corneal power, corneal thickness, astigmatism and irregularity indices (p<0.001 for most comparisons). Agreement varied across parameters, indicating systematic measurement bias despite high correlation.

Conclusions

Although measurements from Pentacam HR, AS - OCT, Cassini and VARIO show strong correlations, significant inter device differences exist. Corneal parameters derived from different devices should not be considered interchangeable in clinical practice or research