A Single-Center Prospective Study Comparing Clinical Outcomes For Three Advanced Techology Presbyopia-Correcting Iols

Comparing visual acuity, defocus curve and patient-reported outcome measures (PROMs) including spectacle independence and patient satisfaction with two partial range of depth of field IOLs Vivity (Alcon), PureSee (Johnson and Johnson Vision) and a full range of depth of field IOL with a spiral optic RayOne Galaxy (Rayner) in cataract or refractive lens exchange eyes.

Single site prospective study - IRCCS Policlinico San Donato Hospital, Milan Italy

Before surgery slit lamp examination, keratometry and biometry, as well as subjective refraction were performed. The follow-up visit at 1 month after surgery included subjective refraction and monocular UDVA and CDVA (4m), UIVA and DCIVA (66cm) and UNVA and DCNVA (40cm) with ETDRS charts, defocus curve analysis and PROMs for patient satisfaction and spectacle independence were assessed using the VF-14 questionnaire.

For RayOne Galaxy (n = 57), PureSee (n = 30) and Vivity (n = 57). Mean UDVA and CDVA were 0.01, 0.02, 0.05 and 0.00, 0.01, 0.00 logMAR, respectively. UIVA and DCIVA were 0.06, 0.16 and 0.12 and 0.07, 0.14, 0.13 logMAR respectively. UNVA and DCNVA were 0.17, 0.31, 0.29 and 0.20, 0.29, 0.34 logMAR respectively. In the defocus curve, mean VA at 0.0 D were -0.04, -0.01 and -0.01, respectively. At -1.5 D mean VA were 0.05, 0.11 and 0.08 logMAR respectively. At -3.0 D mean VA were 0.24, 0.40 and 0.41, respectively. 94% of patients reported to be mostly or fully satisfied with Galaxy, vs. 58% in the PureSee and 70% in the Vivity group. 81% of patients reported spectacle independence for near with Galaxy, vs. 25% for PureSee and 40% for Vivity.

All IOLs demonstrated a good visual performance for distance and intermediate. Better uncorrected and corrected near visual acuities were observed in the Galaxy group. A higher rate of spectacle independence at near visual acuity was achieved in the Galaxy group. Subjective visual disturbance was comparable in all three groups, whereas spectacle independence and patient satisfaction achieved higher scores in the Galaxy group. Our findings in the ongoing trial indicate that the spiral IOL provides high levels of spectacle independence while maintaining a high visual quality and patient satisfaction rates.