ESCRS - PP19.03 - Evaluation Of Axial Length Measurement And Other Biometric Parameters Using Three Different Generations Of Biometers

Evaluation Of Axial Length Measurement And Other Biometric Parameters Using Three Different Generations Of Biometers

Published 2026 - 44th Congress of the ESCRS

Reference: PP19.03 | Type: Free paper | DOI: 10.82333/g84y-yr20

Authors: Dr Ferdinando Cione* 1 , Dr Domenico Mucci 2 , Dr Isabella Pellegrino 2 , Dr Francesco Maria Capuano 2 , A/Prof. Maddalena De Bernardo 3 , A/Prof. Nicola Rosa 3

1University Eye Clinic,AOU San Giovanni di Dio e Ruggi d'Aragona,Salerno,Italy, 2Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana,University of Salerno,Salerno,Italy, 3Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana,University of Salerno,Salerno,Italy;University Eye Clinic,AOU San Giovanni di Dio e Ruggi d'Aragona,Salerno,Italy

Purpose

To compare biometric measurements obtained with partial coherence interferometry (IOLMaster 500, IOLM), optical low-coherence reflectometry (Lenstar 900, LS900), and swept-source optical coherence tomography (Eyestar 900, ES900).

Setting

University Eye Clinic, Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Italy.

Methods

In this prospective, observational study, axial length (AL), anterior chamber depth (ACD), aqueous depth (AD), lens thickness (LT), and central corneal thickness (CCT) were measured with the three devices. Exclusion criteria were ocular disease, previous ocular surgery, and contact lens use within 72 hours. Normality was assessed using the exact Kolmogorov–Smirnov test. Comparisons were performed with paired T-tests and repeated-measures ANOVA with Bonferroni correction. Agreement was evaluated using Bland–Altman plots, Pearson correlation (r), and intraclass correlation coefficients (ICC). Subgroup analysis by eye side was conducted.

Results

Two-hundred-six eyes of 103 healthy subjects (38 females) were included. All devices showed excellent correlation for AL and ACD (r≥0.947, ICC≥0.939; p<0.001). AL and ACD were comparable between LS900 and IOLM (ΔAL=+0.00±0.09mm; ΔACD=+0.01±0.10mm; p>0.050). ES900 measured longer AL and deeper ACD than LS900 (ΔAL=+0.03±0.10mm; ΔACD=+0.04±0.11mm; p≤0.031) and IOLM (ΔAL=+0.03±0.08mm; ΔACD=+0.04±0.11mm; p≤0.013). Strong correlation was observed between ES900 and LS900 for CCT, AD, and LT (r≥0.979, ICC≥0.961; p<0.001). ES900 measured thicker CCT, deeper AD, and thinner LT (p<0.017).

Conclusions

Despite excellent correlation, ES900 provided systematically higher AL and ACD values and different anterior segment measurements. These devices should not be used interchangeably; device-specific interpretation is recommended to optimize refractive outcomes in cataract surgery.