Optical Simulation Of Refractive Power Control Of Intraocular Lens Induced By Femtosecond Laser-Induced Gradient Refraction

Feasibility of optical simulation femtosecond laser-induced gradient refractive index technology for controlling the refractive power of hydrophobic acrylic intraocular lenses (IOLs)

Optical simulation

Based on the Liou Brennan eye model, a simulated eye system containing 21D hydrophobic acrylic ester IOL was constructed in Zemax optical software. Gradient refraction technology was introduced to construct a gradient refractive type plano convex/plano concave lens with a diameter of 5mm in the center of the IOL. The refractive index of the new lens was set to 1.446; Using the damping least squares method to optimize key parameters such as lens curvature radius, with MTF and spherical aberration as core evaluation indicators, the imaging quality of optical systems under different refractive power control is evaluated to verify the effect of femtosecond laser combined with gradient refraction technology on changing IOL refractive power.

The gradient refractive index lens induced by femtosecond laser can achieve precise control of IOL refractive power. Constructing a plano convex lens can reduce IOL optical power by -0.5~-2.0D, while constructing a plano concave lens can increase optical power by+0.5~+2.0D. Under different control schemes, the optimized lens has an MTF value of ≥ 0.452 at the set spatial frequency, meeting the ISO standard (MTF>0.43), and the spherical aberration coefficient remains low, without significantly affecting imaging quality; The amplitude of refractive power regulation is significantly correlated with the curvature radius and thickness of gradient refractive lenses.

Under the set optical simulation conditions, femtosecond laser can achieve safe and controllable control of refractive power by constructing gradient refractive convex/concave lenses inside hydrophobic acrylic IOL, and the imaging quality of the optical system is good after control. This technology provides important experimental support and application potential for non-invasive correction of residual refractive errors after cataract surgery in clinical practice