Visual Outcomes After Bilateral Tecnis Puresee Implantation In Refractive Lens Exchange Patients With Ocular Morbidities: A Multicentre Retrospective Cohort Study.

To describe uncorrected visual outcomes after bilateral implantation of partial range of vision IOL, Tecnis PureSee in refractive lens exchange (RLE) patients with ocular comorbidities, and to compare outcomes across predefined subgroups (laser vision correction [LVC] history, amblyopia, corneal pathology, maculopathy, “others,” and general‑health–related ocular involvement). Primary endpoints were binocular UCDVA, UCIVA, and UCNVA evaluated overall and stratified by comorbidity.

Retrospective, multicentre cohort at tree specialized surgical FYEO refractive centres. Refractive lens exchange with Tecnis PureSee were bilaterally performed between 1 January 2024 and 31 December 2025, assessed at 3‑months post‑operative follow‑up. Data were extracted from the clinical results database.

All bilateral PureSee RLE cases were screened; comorbidity status was captured during the pre‑operative consultation. Unique patients were identified (de‑duplicated by ID), subgroup labels were harmonised and further specified. Characteristics of the subgroups have been analysed. Binocular vision outcomes at distance, intermediate and near were analysed overall and by comorbidity subgroup. Summary measures included n, mean, median, IQR, min–max, and the proportions achieving ≤0.10 and ≤0.20 logMAR for each endpoint (UCDVA/UCIVA/UCNVA). 

946 patients underwent bilateral PureSee; 418 had a recorded ocular comorbidity (LVC 105; amblyopia 52; corneal pathology 101; maculopathy 102; other ocular morbidity 45; general‑health–related ocular involvement 13).

Overall outcomes at ~2 months: UCDVA mean −0.002 logMAR (≤0.10: 88.0%, ≤0.20: 95.7%); UCIVA mean 0.131 (≤0.20: 78.0%); UCNVA mean 0.224 (≤0.20: 45.5%).

By subgroup, near acuity was worst in maculopathy (UCNVA mean 0.273), while distance medians clustered around 0.00 across groups (e.g., Cornea UCDVA mean −0.008; Others −0.035)

Bilateral Tecnis PureSee provided excellent uncorrected distance and good intermediate visual acuity in a real‑world multicentre cohort that included substantial ocular comorbidity; near acuity was most sensitive to macular disease, as expected. These findings support the feasibility of non‑diffractive EDOF IOLs in carefully selected RLE candidates with comorbidity, while highlighting the need to calibrate near‑vision expectations in maculopathy.