Excimer Laser Trabeculostomy Clinical Outcomes And Safety Profile - 6 Month Provisional Outcomes
Published 2026 - 44th Congress of the ESCRS
Reference: PP04.017 | Type: Free paper | DOI: 10.82333/vwbp-wp46
Authors: Annabel Mach* 1 , Mr Tom Ayton 2 , Mr Sameer Trikha 2 , Mr Gerassimos Lascaratos 3 , Ms Modupe Sodeinde 2 , Mr Avinash Kulkarni 2 , Mr Mohammed Abu-Bakra 2 , Mr Andrew Swampillai 2 , Ms Madalina Pavel 2 , Mr Obeda Kailani 3
1King's College London,London,United Kingdom, 2King's College Hospital,London,United Kingdom, 3King's Ophthalmology Research Unit,King's College London,London,United Kingdom
Purpose
To review the clinical outcomes and safety profile of excimer laser trabeculostomy (ELT) in open-angle glaucoma.
Setting
ELT is a form of minimally invasive glaucoma surgery that provides an alternative treatment to traditional surgical methods, lowering intraocular pressure (IOP) with improved recovery times and reducing the need for topical medications.
Methods
Patients who received ELT were reviewed over 6 months in this retrospective study. The primary outcomes were to measure the changes in IOP, number of topical IOP-lowering medications and visual acuity from baseline.
Results
18 patients had ELT, with 22 eyes operated on in total. 21 eyes had phacoemulsification in combination with ELT. The mean IOP at baseline was 15.25 mmHg with a standard deviation (+) of 3.62 mmHg and decreased to 12.82 ± 3.67 mmHg at 3 months (P = 0.0293). Average IOP at 6 months was 14.71 ± 2.93 mmHg (P = 0.7539). The mean number of IOP-lowering eye drops decreased from 1.59 ± 0.73 mmHg to 0.86 ± 0.69 mmHg at 6 months (P = 0.0279). Visual acuity (logMAR) improved from 0.46 ± 0.50 to 0.27 ± 0.38 (P = 0.5889). Complications occurred during 9% of the procedures (n = 2). 27% of patients had post-operative complications, including cystoid macular oedema (n = 3), hyphaema (n = 1), uveitis (n = 2) and episcleritis (n = 1).
Conclusions
ELT combined with phacoemulsification decreased IOP and the number of IOP-lowering eye drops, whilst improving visual acuity. The safety profile and long-term efficacy of this intervention need to be reviewed.