ESCRS - POOTH039 - Clinical Outcomes And Safety Profile Of Single-Incision Refractive Lens Exchange For The Correction Of Refractive Errors And Presbyopia: A Real-World Data Analysis

Clinical Outcomes And Safety Profile Of Single-Incision Refractive Lens Exchange For The Correction Of Refractive Errors And Presbyopia: A Real-World Data Analysis

Published 2026 - 44th Congress of the ESCRS

Reference: POOTH039 | Type: Free paper | DOI: 10.82333/b8pf-k446

Authors: Dr Chi Xiao* 1

1Dongguan Guangming Ophthalmic Hospital,dongguan,China

Purpose

To evaluate the efficacy, safety, and patient satisfaction of single-incision refractive lens exchange (RLE) in achieving full-range of vision for patients with refractive errors and presbyopia in a real-world setting.

Setting

A single-center retrospective study.

Methods

This real-world analysis included 50 eyes of 25 patients (mean age 49 ± 4.28 years) who underwent single-incision RLE. The study cohort comprised patients with ametropia and presbyopia. The mean preoperative spherical equivalent (SE) was -8.30 ± 3.23 D (range: -18.25 D to -2.75 D). Preoperative mean ADD, AMP, and DLI were 1.24 ± 0.41 D, 3.17 ± 0.58 D, and 6.18 ± 2.97, respectively. Preoperative and postoperative (6 months) uncorrected and corrected visual acuities at distance (UDVA, CDVA), intermediate (60cm), and near (40cm) were analyzed. Refractive outcomes, defocus curves, and patient-reported satisfaction/spectacle independence were assessed. Intraoperative and postoperative complications were recorded.

Results

The procedure demonstrated an excellent safety profile with no complications observed. Postoperative refractive predictability was high, with a mean SE of +0.12 ± 0.33 D; 92% and 100% of eyes were within ±0.25 D and ±0.50 D of target, respectively. Uncorrected vision improved significantly at all distances: UDVA to 1.02 ± 0.09, intermediate (60cm) to 1.04 ± 0.11, and near (40cm) to 0.94 ± 0.06. The safety and efficacy indices were 1.14 and 1.08. Patient satisfaction was 100%, with spectacle independence rates of 100% (distance), 96% (intermediate), and 100% (near). Defocus curves confirmed an extended depth of focus.
 

Conclusions

In this real-world cohort, single-incision RLE proved to be a highly effective, predictable, and safe procedure for correcting refractive errors and presbyopia, with zero complications observed in this series. It provided excellent full-range uncorrected visual acuity, high levels of patient satisfaction, and complete spectacle independence for distance and near vision, with outcomes comparable to or exceeding those of standard refractive surgeries.