Outcomes Of A Novel Artificial Endothelial Implant (Endoart) For Treating Chronic Corneal Edema
Published 2026 - 44th Congress of the ESCRS
Reference: POCOR288 | Type: Free paper | DOI: 10.82333/kgry-ab23
Authors: Dr Carlos Lisa* 1 , Dr LUIS FERNANDEZ-VEGA CUETO 1 , Dr BELEN ALFONSO-BARTOLOZZI 1 , Dr LUCIA IBARES 1 , Dr JOSE F. ALFONSO 1
1Instituto Fernández-Vega,Oviedo,Spain
Purpose
To report the outcomes of a novel artificial endothelial implant (EndoArt) for treating chronic corneal edema.
Setting
Instituto Universitario Fernández-Vega (Oviedo), España
Methods
Patients with poor prognosis for graft survival and chronic corneal edema underwent removal of the Descemet membrane or previous endothelial graft and implantation of an artificial endothelial replacement membrane (EndoArt, EyeYon Medical, Israel). The implant was secured to the posterior corneal surface using an air–gas bubble and a nylon suture. Main outcome measures included central corneal thickness, corrected distance visual acuity, rate of rebubbling, device related complications and ocular discomfort with at least one year of follow-up.
Results
30 eyes of 29 patients underwent EndoArt implantation.Central corneal thickness significantly decreased from a mean of 859 ± 178 μ preoperatively to 681 ± 187 μ postoperatively. Marginal improvement in visual acuity was obtained due to severe ocular comorbidities and previous chronic stromal fibrosis. The average CDVA pre-op was 1.88 ± 0.74 (logMar) and improved to 1.40 ± 0.89 (logMar) after the surgery. Early device dislocation happened in 45% of the cases. The rebubbling rate was 42.3 %.Two eyes with previous failed penetrating keratoplasty had extreme thinning with total recovery in one case and perforation after 2 years in the other case.We had EndoArt failure in another 3 eyes.
Conclusions
EndoArt implantation improves central thickness and corneal transparency in patients with bullous keratopathy and poor prognosis for a endothelial or penetrating keratoplasty.