Early Experience Of Endoart In The United Kingdom: A Case Series Of 10 Eyes
Published 2026
- 44th Congress of the ESCRS
Reference: POCOR273
| Type: Free paper
| DOI:
10.82333/8vzd-6592
Authors:
Mr Leo Feinberg* 1
, Ms Poonam Sharma 2
, Mr Shakeel Ahmad 2
, Mr Harry Roberts 1
1Royal Devon University Hospitals NHS Foundation Trust,Exeter,United Kingdom;Faculty of Health and Life Sciences,University of Exeter,Exeter,United Kingdom, 2Royal Devon University Hospitals NHS Foundation Trust,Exeter,United Kingdom
Purpose
To evaluate the safety and efficacy of the EndoArt® artificial endothelial implant in patients unsuitable for conventional endothelial keratoplasty.
Setting
University teaching hospital in the United Kingdom.
Methods
This retrospective interventional case series included 10 eyes of 10 patients undergoing EndoArt® implantation between December 2024 and September 2025. Primary outcome measures were best-corrected visual acuity (BCVA) and central corneal thickness (CCT). Secondary outcomes included additional interventions and incidence of adverse events.
Results
Six patients (60%) had previous keratoplasty; four (40%) had multiple (2–4) failed grafts. Nine (90%) had prior glaucoma filtration surgery and three (30%) were aphakic. Surgery was for visual rehabilitation in four eyes (40%) and symptom relief in six (60%). Mean follow-up was 7.3 months (3–14). Five eyes (50%) required ≥1 re-intervention and four needed multiple (2–4). All implants were attached at final review.
Mean BCVA and CCT improved from 1.95 logMAR and 787±93 µm pre-operatively to 1.78 logMAR and 658±185 µm post-operatively. In visual cases, BCVA improved from 1.67 to 0.76 logMAR and CCT from 786±112 to 603±138 µm. All comfort cases had complete symptom resolution.
Conclusions
EndoArt® offers a promising donor-free option for highly complex eyes unsuitable for keratoplasty. Early outcomes are influenced by the substantial comorbidity burden of this cohort.