Endogenous Endophthalmitis Secondary To Liver Abscess: Diagnostic And Therapeutic Challenges

To report a clinical case of endogenous endophthalmitis secondary to liver abscess and emphasize the importance of early systemic evaluation and multidisciplinary management in patients presenting with severe intraocular inflammation.

Department of Ophthalmology, Vinnytsia Regional Clinical Hospital named after M.I. Pirogov, Vinnytsia, Ukraine. Multidisciplinary management involving ophthalmologists and general surgeons.

A patient presented with acute ocular pain, redness, and rapid visual deterioration. Ophthalmic examination revealed severe intraocular inflammation consistent with endogenous endophthalmitis. Further systemic evaluation identified a liver abscess as the primary infectious focus. The patient underwent surgical drainage of the liver abscess. Intravitreal antibiotic therapy with vancomycin was administered along with systemic antibacterial treatment. Multidisciplinary management was initiated involving ophthalmologists and general surgeons. Prompt identification of the systemic infection allowed early targeted treatment and control of the infectious process.

Endogenous endophthalmitis is a rare but vision-threatening condition that may occur secondary to systemic infections such as liver abscess. Early diagnosis, prompt intravitreal antibiotic therapy, and management of the primary infectious focus are essential for improving both ocular and systemic outcomes. Ophthalmologists should consider systemic infectious sources when evaluating patients with severe intraocular inflammation.