ESCRS - POCOR013 - Salmon Patch-Like Conjunctival Lesion Secondary To Long-Term Administration Of Topical Brimonidine: A Case Report

Salmon Patch-Like Conjunctival Lesion Secondary To Long-Term Administration Of Topical Brimonidine: A Case Report

Published 2026 - 44th Congress of the ESCRS

Reference: POCOR013 | Type: Case Report | DOI: 10.82333/pem9-q690

Authors: Dr Rakan Alessa* 1

1Ophthalmology,National Guard Health Affairs,riyadh,Saudi Arabia

Purpose

Brimonidine is a commonly used intra-ocular pressure-lowering agent for glaucoma patients. Allergic follicular or papillary conjunctivitis is a well-known side effect of brimonidine. Brimonidine is associated with ocular allergic symptoms such as conjunctival hyperemia, stinging sensation, photophobia and, in severe cases, corneal erosions. Here, we report a case of atypical conjunctival lesion following long-term administration of brimonidine. 

Setting

NA

Report of case

We report the clinical findings of a 72-year-old female presenting with a salmon patch-like conjunctival lesion affecting the bulbar and palpebral conjunctiva after long-term use of brimonidine. The finding was suspicious of conjunctival lymphoproliferative disorders. However, upon cessation of brimonidine, along with the administration of short-course topical steroid, a complete resolution of the lesion was evident. Biopsy was not performed as the clinical picture improved with conservative management. No recurrence was observed over 1 year follow up. 

Conclusion/Take home message

Careful observation is recommended for patients with a history of long-term use of brimonidine for the development of atypical conjunctival lesions which may simulate the appearance of conjunctival lymphoproliferative disorders.