Propensity-Matched Comparison Of Rayone Galaxy And Rayone Monofocal Intraocular Lenses In A Large Real-World Cataract Surgery Cohort
Published 2026 - 44th Congress of the ESCRS
Reference: POCAT476 | Type: Free paper | DOI: 10.82333/fgxx-xf50
Authors: Prof. Mahmut Dogramaci 1 , Ms Selin Dogramaci* 2 , Mr Tom Critchley 3 , Ms Kendall Johnston 4 , Mr Alexander Silvester 5 , Mr Stephen Mcatamney 5
1Ophthalmology,Spamedica Hospitals,Chelmsford,United Kingdom, 2Medical School, University of Buckingham ,Buckingham ,United Kingdom, 3Ophthalmology,Spamedica Hospitals,Manchester,United Kingdom, 4Ophthalmology,Freedom Vision ,Colchester,United Kingdom, 5Ophthalmology,Spamedica Hospitals,Bolton,United Kingdom
Purpose
To compare postoperative visual outcomes between the RayOne Galaxy intraocular lens and the RayOne monofocal intraocular lens in a large real-world cataract surgery cohort.
Setting
Spamedica hospitals and Freedom Vision
Methods
A retrospective multicentre dataset analysis of 5654 eyes undergoing cataract surgery with Rayner intraocular lenses. Eyes implanted with RayOne Galaxy lenses (including toric models) were compared with eyes implanted with RayOne monofocal lenses. Propensity score matching was performed using preoperative uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal astigmatism derived from keratometry, and axial length to generate balanced comparison cohorts. Postoperative UDVA, CDVA, and visual acuity improvement were compared between groups. Multivariable regression analysis was used to evaluate the independent association between intraocular lens type and postoperative visual outcomes.
Results
Propensity matching generated balanced cohorts of 418 eyes per group with excellent baseline balance across all matching variables (standardised mean differences <0.06). Postoperative UDVA was significantly better in the RayOne Galaxy group compared with RayOne monofocal lenses (mean logMAR 0.075 vs 0.146), with greater visual acuity improvement (0.451 vs 0.364 logMAR, p < 0.001). There was no significant difference in postoperative CDVA between groups (0.057 vs 0.054 logMAR, p = 0.80). Multivariable regression analysis confirmed that RayOne Galaxy lens was independently associated with improved postoperative UDVA (β = −0.066 logMAR, p < 0.001) after adjustment for baseline visual acuity, axial length, and corneal astigmatism.
Conclusions
In this large real-world cohort, the RayOne Galaxy intraocular lens demonstrated significantly better uncorrected distance visual acuity and greater improvement in postoperative vision compared with a conventional RayOne monofocal lens, while maintaining equivalent corrected visual acuity. These findings support the optical advantage of the RayOne Galaxy design in improving functional visual outcomes following cataract surgery.