ESCRS - POCAT421 - Comparative Outcomes Of The Next-Generation Monofocal Enhanced Depth-Of-Focus Intraocular Lens: Intermediate Optimized Iol, Envista Aspire (Bausch & Lomb ) And Enhanced Monofocal Intraocular Lens Eyhance (Johnson And Johnson )In Cataract Sur

Comparative Outcomes Of The Next-Generation Monofocal Enhanced Depth-Of-Focus Intraocular Lens: Intermediate Optimized Iol, Envista Aspire (Bausch & Lomb ) And Enhanced Monofocal Intraocular Lens Eyhance (Johnson And Johnson )In Cataract Surgery

Published 2026 - 44th Congress of the ESCRS

Reference: POCAT421 | Type: Free paper | DOI: 10.82333/m9js-yg64

Authors: Dr MARIA CATERINA CASCELLA* 1 , Dr NICOLO' SANTOSTASI 2 , Dr VASILEIOS PEPONIS 3 , Dr IOANNIS DATSERIS 4 , Dr FRANCESCA PALMITESSA 1 , Dr FEDERICA MARZULLI 1 , A/Prof. ANNA MARIA ROSZKOWSKA 5

1NEUROSENSORY DEPARTMENT,OPHTALMOLOGY UOSVD -F.JAIA HOSPITAL,CONVERSANO-BARI,Italy, 2DEPARTMENT OF HUMAN PATHOLOGY of ADULTS and DEVELOPMENTAL AGE ,MESSINA UNIVERSITY ,MESSINA,Italy, 3EYE DEPARTMENT ,OPHTHALMIATREIO,ATHENS ,Greece, 4OPHTALMOLOGICAL INSTITUTE ,OMMA OPHTALMOLOGICAL INSTITUTE OF ATHENS ,ATHENS ,Greece, 5DEPARTMENT OF BIOMEDICAL and DENTAL SCIENCES,OPHTALMOLOGY and MORPHOLOGICAL -FUNCTIONAL IMAGING,MESSINA UNIVERSITY ,MESSINA,Italy

Purpose

 

To evaluate refractive outcomes, defocus curve, wavefront analysis, automated refraction of novels monofocal-PLUS intraocular lenses (IOL) with higher order aspheric coefficients and controlled curvature change in a retrospective multicentric study of 1 year follow up,(primary endpoint). Further to analyze to what extent do these new lenses ,introduced to the market to adress the limitation of monofocal-lenses (that provide optimal uncorrected visual acuity at a fixed distance), allow daily spectacle independence(secondary endpoints)

 

Setting

1-NEUROSENSORY DEPARTMENT OF  OPTHALMOLOGY-  UOSVD -F.JAIA HOSPITAL, CONVERSANO-BARI, ITALY

2-DEPARTMENT OF BIOMEDICAL ,DENTAL SCIENCES ,OPTHALMOLOGY AND MORPHOLOGICAL -FUNCTIONAL IMAGING ,
MESSINA -ITALY

3-DEPARTMENT  OF HUMAN PATHOLOGY OF ADULTS AND DEVELOPMENTAL AGE-(Gaetano Barresi)- EYE CLINIC -MESSINA -ITALY

4-EYE DEPARTMENT , OPHTHALMIATREIO, OPHTALMOLOGICAL INSTITUTE of  ATHENS , ATHENS -GREECE

5-OMMA -OPHTALMOLOGICAL INSTITUTE OF ATHENS , ATHENS , GREEC

 

Methods

 

Multicenter retrospective study included180 healthy eyes(with astigmatism pre-op less than 0.75D) from 90pts aged from 45 to 75 yo,undergone cataract surgery, Aspire IOL(B&L) implantation,compared to other180 healthy eyes from 90pts,same average age,implanted by Eyhance IOL.(J&J) Micromonovision(offset of-0.50to -075D)was performed to achieve superior outcomes at near and intermediate distance.Outcome measures included monocular/binocular uncorrected(UDVA)/corrected(CDVA)distance,intermediate(UIVA-CIVA)(at 66 cm)and near (U/CNVA)(at 40 cm)visual acuity,defocus curve,contrast sensitivity,automated manifest(MRSE) refraction spherical equivalent,subjective aberrations perceptions by questionnaires(PREM &PROM).Follow-up at 1-3-6-9-12 months.

 

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Results

Patient-reported visual symptoms did not differ between two groups( low rates of glare and halos).The mean(standard deviation [SD]) binocular UNVA (uncorrected near visual acuity)is equal in both group at 1month: a greater proportion(69%)of patients achieved binocular UNVA of 20/25 or better.The mean(SD)monocular UNVA and UIVA(uncorrected intermedate visual acuity)showed a slight,but non-significant advantage in the Aspire group(0.26 [0.15] logMAR vs Eyhance-group 0.29 [0.15] logMAR; P >0.05).These IOLs with the micromonovision approach have potential advantage,they should enable larger myopic off-set in non-dominant eye.Data reported superior intermediate and near vision compared to the bilateral emmetropia of the same monofocal-plus lens

 

Conclusions

To address the challenges,new technologies have emerged to improve IOL performance minimizing the unwanted photic phenomena,commonly associated with multifocal IOLS.MonofocalPLUS Enhanced depth-of-focus IOLs have developed to bridge the gap between monofocal/multifocal IOLs. Its seemed to provide a more seamless,continuous range of focus across intermediate to far distances,elongating the focal points to offer an enhanced and continuous range of vision. ASphire as Eyance IOLs provides marginally improved intermediate vision with photic phenomena comparable to conventional monofocals,no statistically difference between both implant.In optical valuetion testing enVista Aspire seems less sensitive to tilt or decentration compared with Eyhance.