Safety And Effectiveness Of A Novel Extended Depth Of Focus Intraocular Lens With A Unique Virtual Aperture Optic Following Bilateral Cataract Surgery
Published 2026 - 44th Congress of the ESCRS
Reference: POCAT396 | Type: Free paper | DOI: 10.82333/sgxy-yx04
Authors: Dr Francisco Sanchez Leon* 1 , Dr Rocio Sanchez Sanoja 1 , Dr Luis Fernando Martiz 2 , Dr Francisco Sanchez Sanoja 3
1Anterior Segment,Novavision Laser Center,Naucalpan ,Mexico, 2Ministerio de Salud Panamá,MINSA ,Panama,Panama, 3Oftalmología,Fund. Conde de Valenciana,Ciudad de Mexico,Mexico
Purpose
To evaluate the safety and effectiveness of the Z+ intraocular lens (virtual small aperture IOL) for the correction of aphakia and mitigation of presbyopia by providing an extended depth of focus following cataract extraction
Setting
Novavision Laser Center, Mexico City
Methods
This was a prospective, open-label, consecutive case series of 33 subjects aged 40–75 years, who underwent bilateral cataract surgeries with IOL implantation by a single surgeon at an ophthalmology surgical center in Mexico during 2023–2024. Vision and safety outcomes were evaluated through 6 months. Main safety outcomes were intraoperative and postoperative AEs and dysphotopsia type/severity. Main effectiveness outcomes were percent of eyes with monocular BCDVA of 0.3 logMAR (20/40 Snellen) or better, and binocular uncorrected acuity of 0.2 logMAR (20/32 Snellen) or better, at all distances. Secondary effectiveness outcomes included acuity under low-contrast and mesopic conditions.
Results
Data are from 66 eyes/33 subjects of mean age=64.1 years. No serious AE occurred in any eye/subject; 100% of subjects were halo-free and 79% were glare-free at 6 months. All eyes achieved BCDVA equal to/better than 0.3 logMAR, averaging 0.06±0.06 logMAR; 47% reached 20/20 Snellen BCDVA. Mean UCDVA was 0.16±0.08 logMAR. Mean UCNVA was 0.17±0.12 logMAR. Mean mesopic acuity was barely reduced: UCDVA=0.18±0.11 logMAR, BCDVA=0.08±0.08 logMAR, and UCNVA=0.18±0.11 logMAR (p>0.05 for all photopic comparisons). At 10% contrast, 58% of eyes showed UCIVA better than 0.3 logMAR (20/40 Snellen). Binocular VA was equal to/better than 0.2 logMAR (20/32 Snellen) in all subjects at all focal ranges.
Conclusions
The Z+ IOL safely provided outstanding distance vision outcomes, but also good acuity at intermediate and near focal distances, with well-maintained acuity under mesopic lighting and acceptable low-contrast acuity. Patient satisfaction was high, halos did not occur, and glare was markedly reduced from preoperative levels.