Efficacy, Safety And Predictability Of A Biaspheric Extended Depth Of Focus Intraocular Lens In Glaucoma Patients
Published 2026 - 44th Congress of the ESCRS
Reference: POCAT391 | Type: Free paper | DOI: 10.82333/w6kp-jw76
Authors: Dr Ignacio Rodriguez-Una* 1 , Andres Fernandez-Vega-Cueto 2 , Luis Fernandez-Vega-Cueto 2 , Maria E. Simancas 2 , Jose F. Alfonso 2
1Fernandez-Vega Ophthalmological Institute,Oviedo,Spain;Fundacion de Investigacion Oftalmologica,Oviedo,Spain, 2Fernandez-Vega Ophthalmological Institute,Oviedo,Spain
Purpose
To evaluate visual outcomes, refractive predictability, and safety of a biaspheric extended depth of focus (EDOF) intraocular lens (IOL) in patients with mild to moderate glaucoma undergoing cataract surgery.
Setting
Fernandez-Vega Institute, Spain.
Methods
A retrospective study including glaucoma patients who underwent phacoemulsification with implantation of an Asqelio™ EDOF IOL (AST VisionCare Inc., USA). Eyes with previous glaucoma surgery were excluded. Preoperative and 6-month postoperative assessments included refraction, uncorrected and corrected distance visual acuity (UDVA, CDVA), intraocular pressure (IOP), number of topical hypotensive medications, and visual field mean deviation (MD).
Results
Thirty-seven eyes of 24 patients (mean age 68.1±7.1 years) were analyzed. Glaucoma was mild in 84% and moderate in 16% of eyes; 57% underwent combined minimally invasive glaucoma surgery (MIGS). Mean spherical equivalent improved from -0.35±2.08 D preoperatively to -0.03±0.42 D postoperatively. UDVA and CDVA improved from 0.43±0.29 and 0.84±0.25 to 0.80±0.23 and 0.94±0.12, respectively (p<0.01). Efficacy and safety indices were 1.0 and 1.1. Predictability showed 89% of eyes within ±0.50 D. Mean IOP decreased from 18.8±7.8 to 14.3±3.4 mmHg (p<0.05), with no visual field progression. Topical hypotensive medications decreased from 1.7±1.1 to 0.6±0.9.
Conclusions
Implantation of this biaspheric EDOF IOL with a posterior-surface phase-ring design provided good visual performance, refractive predictability, and safety in selected glaucoma patients, with satisfactory IOP control and stable visual fields. This IOL may be considered in mild to moderate glaucoma, particularly when combined with MIGS.