Comparative Analysis Of Visual Outcomes, Defocus Profile And Patient Reported Outcomes Of Tecnis Puresee And Clareon Vivity Non-Diffractive Extended Depth-Of-Focus Intraocular Lenses

This prospective observational comparative study included 48 patients without significant corneal astigmatism (<1.0 D) or ocular comorbidity undergoing bilateral cataract surgery with Tecnis PureSee (n=28) or Clareon Vivity (n=20), implanted by a single experienced surgeon. At 6 months, binocular distance corrected distance (4 m), intermediate (66 cm), and near (40 cm) visual acuities (ETDRS) were assessed. Binocular defocus curves (+2.00 to −4.00 D, 0.50 D steps) were obtained. Functional defocus range was defined as visual acuity ≤0.20 logMAR. Contrast sensitivity, Quality of Vision, and Catquest-9SF questionnaires were evaluated. Statistical analysis was performed using t test or Wilcoxon test as appropriate (STATA 17.0).

Both IOLs achieved excellent binocular distance vision (Vivity: −0.01±0.05 logMAR vs PureSee: 0.00±0.03 logMAR; p=0.213). Distance-corrected intermediate acuity had a mean of 0.07±0.09 logMAR for Vivity and 0.15±0.08 logMAR for PureSee (p=0.001), while distance-corrected near acuity was comparable (Vivity: 0.25±0.11 vs PureSee: 0.24±0.10 logMAR; p=0.704). Defocus curves differed at −1.0 D (Vivity: 0.02 ± 0.04 logMAR, PureSee: 0.07 ± 0.07 logMAR; p=0.039) and −1.5 D (Vivity: 0.06 ± 0.06 logMAR, PureSee: 0.13 ± 0.10 logMAR; p=0.015). Functional defocus range was similar with 3.34 D for Vivity and 3.38 D for PureSee. Glare was more frequent with Vivity (20% vs 7%; p=0.034). Contrast sensitivity and Catquest-9SF were comparable (p>0.05).