Extended Depth Of Focus Intraocular Lens Implantation In A Patient With Retinitis Pigmentosa: A Case Report And Management Of Postoperative Capsular Fibrosis
Published 2026 - 44th Congress of the ESCRS
Reference: POCAT054 | Type: Case Report | DOI: 10.82333/kyfh-e458
Authors: Ms Shahzoda Jurakhonova* 1 , Dr Bekzod Shukurov 2 , A/Prof. Jamshid Mamatov 3 , Dr Hikmatullo Sodiqov 4 , Dr Mutabar Yuldasheva 2 , Ms Madina Sharipova 5
1medical school,Central Asian University,Tashkent,Uzbekistan;opthalmology,Optimed Medical Center,Tashkent,Uzbekistan, 2opthalmology,Optimed Medical Center,Tashkent,Uzbekistan, 3opthalmology,AKFA MEDLINE university hospital,Tashkent,Uzbekistan, 4opthalmology,Koz Nuri clinic,Tashkent,Uzbekistan, 5medical school,Central Asian University,Tashkent,Uzbekistan
Purpose
This case report evaluates the feasibility and clinical outcomes of extended depth of focus (EDOF) intraocular lens (IOL) implantation in a 36-year-old male with inherited retinitis pigmentosa (RP), contrary to traditional recommendations favoring monofocal IOLs. It further describes the use of preoperative Alloplant therapy as an additional approach prior to cataract surgery in patients with RP to reduce the risk of retinal complications and discusses the surgical management of post-operative central anterior capsular fibrosis. This case aims to provide clinical insights into IOL selection in RP patients and complication management.
Setting
The case was managed at Optimed Medical Center, a tertiary ophthalmology clinic in Tashkent, Uzbekistan, equipped for advanced cataract and retinal diagnostics and surgical interventions.
Report of case
A 36-year-old male with a history of inherited retinitis pigmentosa (RP) presented with a complicated mature cataract (Grade 3) in the left eye, associated with vitreoretinal traction, and an incipient cataract in the right eye. Preoperative BCVA was 1.52 LogMAR in the left eye and 1.0 LogMAR in the right eye.
Alloplant injection was administered preoperatively in the left eye to reduce the risk of retinal complications, although its effect on retinal stability remains exploratory. with implantation of an EDOF IOL was performed in the left eye at the patient’s informed request, following detailed counseling regarding the limited evidence either supporting or opposing EDOF IOL use in patients with retinitis pigmentosa.
Postoperatively, BCVA improved to 0.52 LogMAR within a week. However, BCVA declined to 0.8 LogMAR by the second postoperative week due to posterior capsule opacification. At three weeks, further deterioration to 1.3 LogMAR was attributed to dense central anterior capsular fibrosis.
Nd:YAG laser capsulotomy was avoided due to the thickness of the fibrotic tissue and the associated risk of IOL damage. Surgical excision of the fibrotic tissue was therefore performed. At five months following cataract surgery, BCVA stabilized at 0.8 LogMAR, with no recurrence of anterior capsular fibrosis. Mild structural improvements were observed on optical coherence tomography (OCT). Nd:YAG laser capsulotomy for residual posterior capsule opacification is planned for March 2026.
Conclusion/Take home message
This case underscores the potential feasibility of EDOF IOL implantation in a patient with retinitis pigmentosa, demonstrating visual improvement despite the occurrence of post-operative complications.The use of Alloplant therapy was part of an individualized treatment strategy, although its role in retinal stability remains exploratory.The successful surgical management of post-operative capsular fibrosis highlights
important clinical considerations for managing rare but vision-limiting complications. These findings suggest that, in carefully selected patients, alternative IOL options may be considered alongside standard monofocal lenses, with thorough patient counseling and realistic expectation setting. Further investigation is required.