ESCRS - FP30.15 - Double Lenticule Transplantation In Advanced Keratoconus With Chronic Corneal Hydrops

Double Lenticule Transplantation In Advanced Keratoconus With Chronic Corneal Hydrops

Published 2026 - 44th Congress of the ESCRS

Reference: FP30.15 | Type: Free paper | DOI: 10.82333/zkt3-r108

Authors: Ms Ceren Ece Semiz* 1 , Faruk Semiz 1 , Fetih Furkan Arslan 2 , Gökçe İdil Semiz 1 , Njomza Hima Musa 1

1Eye Hospital,Prishtina,Kosovo, 2Ophthalmology,Cerrahpaşa-Istanbul University,Istanbul,Türkiye

Purpose

To evaluate the clinical efficacy and safety of double lenticule transplantation in keratoconus patients with chronic corneal hydrops.

Setting

Eye Hospital, Kosovo

Methods

This study included 24 keratoconus eyes with chronic corneal hydrops following prior corneal crosslinking, all of which were indicated for penetrating keratoplasty. The cohort consisted of 24 patients (mean age 21.2 ± 2.5 years; 13 males, 11 females). All underwent double lenticule transplantation with one full lenticule (134.2 ± 18.0 µm, −6.70 ± 0.91 D) and one semi-moon lenticule (149.4 ± 14.6 µm), customized to astigmatism. Lenticules were transplanted through an intrastromal pocket with 130 µm cap thickness. The target minimum postoperative central corneal thickness was 460 µm. All patients were followed for at least 12 months.

Results

At 1 year, UDVA and CDVA improved markedly (1.73 ± 0.24 to 0.76 ± 0.17 and 0.42 ± 0.07 logMAR). Q value improved (–0.75 ± 0.05 to –0.62 ± 0.04), keratometry decreased (K1/K2: 71.7/61.0 D to 66.8/61.0 D), and CCT increased (348.0 ± 20.3 to 482.5 ± 8.7 µm). No complications or rejection occurred.

Conclusions

Double lenticule transplantation using one full and one semi-moon lenticule is a safe and effective alternative to penetrating keratoplasty, providing stromal thickening, maintaining corneal clarity, and improving visual acuity in keratoconus eyes with chronic hydrops.