Comparison Of Visual Outcomes Between Two Presbyopia-Correcting Intraocular Lenses

To compare visual acuity outcomes in patients bilaterally implanted with trifocal (Clareon PanOptix) intraocular lens (IOL) or trifocal (enVista Envy) IOL.

Multi-site, multi-surgeon study within the United States

An ambispective, multi-site study of patients bilaterally implanted with Clareon PanOptix IOL or enVista Envy IOL. A total of 20 subjects in each group were brought back for clinical evaluation between 2.5 and 5-months post-surgery. Clinical evaluations included binocular photopic high contrast uncorrected and distance-corrected (DC) VAs, binocular photopic low contrast (25%) DCVAs and binocular mesopic high contrast DCVAs at distance, intermediate (66 cm), and near (40 cm and 33 cm), binocular mesopic contrast sensitivity, and spectacle independence.

Binocular photopic BCDVA, DCIVA, DCNVA 40 and 33 cm: (P) 0.00±0.05, 0.02±0.05, 0.12±0.12, and 0.16±0.08, respectively; (E) -0.01±0.08, 0.08±0.09, 0.13±0.09, and 0.24±0.12.  Similar low contrast BCDVA and DCNVA were observed except the DCIVA and DCNVA (33 cm): (P) 0.24±0.07, 0.40±0.15 (E) 0.30±0.12, and 0.48±0.12.  Under the mesopic condition, (P) provided about 4.5~ 8.5 letter better DCVA at intermediate and near.  PanOptix provided similar mesopic CS with or with glare at 3,6 and 12 cpd.  Spectacle independence in bright light for D, I, and N were: (P) 95%, 95%, and 95% respectively; (E) 95%, 95%, and 85% respectively.  Dim light all percentages were the same, except (E) was 65% at near.

This ambispective study demonstrated good range of vision from distance to near for both PanOptix and Envy trifocal IOLs with PanOptix showing better intermediate and near distance corrected visual acuities, especially under mesopic condition.