ESCRS - FP01.12 - Defocus Profiles Using A Pyramidal Wavefront -Sensor Based Aberrometer

Defocus Profiles Using A Pyramidal Wavefront -Sensor Based Aberrometer

Published 2026 - 44th Congress of the ESCRS

Reference: FP01.12 | Type: Free paper | DOI: 10.82333/8k9j-nk54

Authors: Dr Elizabeth Law* 1 , Dr Alexander Fraser 2 , Prof. James Myerscough 1

1Ophthalmology,Southend University Hospital,Southend on Sea,United Kingdom;Ophthalmology,Southend Private Hospital,Southend on Sea,United Kingdom, 2Ophthalmology,Southend University Hospital,Southend on Sea,United Kingdom

Purpose

Assesment of defocus profiles is a time-consuming but valuable post-operative assessment in cataract surgery and refractive lens exchange, particularly when increased range of focus has been targeted with the use of advanced intraocular lenses. This study aims to compare subjective defocus measurements for three differing IOL designs with defocus data obtained using the CSO Osiris waverfront sensor-based aberrometer. 

Setting

Southend University Hospital, Essex, United Kingdom

Methods

This retrospective study assessed 60 eyes following implantation of the RayOne Galaxy IOL, Tecnis Eyhance IOL and Ophthalmo Pro Zoe IOL. All subjects were assessed at a 3 month post-operative visit. Unaided and distance corrected visual acuity was measured using ETDRS LogMAR charts, Monocular defocus was assessed subjectively with imposed defocus of +1.50D to -4.00D in 0.5D steps, with additional steps at 0.25D and -0.25D, using established protocols. The Osiris aberrometer was using to create a defocus profile from +1.95 to -5.00 in 0.05D steps, and corresponding points to subjective data were considered. 

 

Results

Following implantation of the Eyhance IOL (n=20), mean uncorrected distance visual acuity(UDVA) was 0.20±0.16LogMAR, and corrected distance visual acuity (CDVA) was 0.05±0.08. Second order polynomial curves were fitted to both subjective and objective defocus data, y=0.01x2 -0.11x+0.45, and y=0.01x2 -0.11x+0.62 respectively. Difference in constants 0.17, was similar to difference in UDVA and CDVA. 

The Zoe IOL (n=20), mean UDVA was 0.35 ± 0.14LogMAR and CDVA was 0.09 ± 0.07, a mean difference of 0.28. Polynomial

y = 0.01x2 - 0.11x + 0.42, was similar, yet pronounced differences were noted through the near range

There was no correlation between defocus with the RayOne Galaxy, particularly throughout the intermediate and near range. 

Conclusions

The CSO Osiris aberrometer provides a useful tool for plotting defocus profile with monofocal IOLs utilising spherical aberration to elongate range of focus, with a slight underestimation of near performance in comparison to subjective data.

However the spiral refractive track of the RayOne Galaxy, is a more compex optic and as such, the aberrometry predicted defocus profile is not an accurate estimation of real world performance