Comparison Of Pupil Size And Axial Length Independence Between An Enhanced Monofocal Iol And A Standard Aspheric Monofocal Iol

Published 2025 - 43rd Congress of the ESCRS

Reference: PP13.02 | Type: Poster | DOI: 10.82333/zym9-gw74

Authors: Ramin Khoramnia* ¹ , Alvin S Relucio ²

¹Department of Ophthalmology,Carl Gustav Carus Dresden University Hospital,Dresden,Germany;Department of Ophthalmology,University of Heidelberg,Heidelberg,Germany, ²HOYA Surgical Optics,Singapore,Singapore

Purpose

To compare the effects of varying pupil sizes and different axial lengths (AL) on monocular distance-corrected intermediate visual acuity (DCIVA) between Vivinex Impress enhanced monofocal intraocular lens (IOL) and AcrySof IQ standard aspheric monofocal IOL.

Setting

COMP TRIAL. N=144. Germany (Augen- und Laserklinik Castrop-Rauxel, Charité Berlin, MVZ Augenklinik Petrisberg, Universitäts-Augenklinik Heidelberg, Universitätsklinikum Freiburg, Universitätsklinikum Knappschaftskrankenhaus Bochum, Universitätsmedizin Mainz), Philippines (Asian Eye Institute Rockwell, Peregrine Eye Laser Inst),

Poland (Centrum Diagnostyki I Mikrochirurgii Oka LENS, Centrum Medyczne), Spain (Clínica Oftalvist Jerez, Clínica Oftalvist Madrid, University Hospital Ramón y Cajal).

Methods

A prospective, multi-center, active-controlled, 2:1 randomized trial with bilateral implantation of Vivinex Impress (test, n=98) or AcrySof IQ (control, n=46). The mean monocular DCIVA for the first eyes were assessed on month 12.

First eyes were categorized into three photopic distance-fixed pupil size sub-groups (small, <3.5 mm; medium, 3.5 to <4.5 mm; large, ≥4.5 mm) and also into three AL sub-groups (short, ≤23 mm; medium, >23 to <24 mm; long, ≥24 mm). The mean DCIVAs for each arm were presented by pupil size and AL sub-groups.

The sub-groups in each category were subsequently examined using regression model–adjusted mean DCIVA to control for the impact of significant predictor variables on DCIVA.

Results

The mean DCIVA benefit for the test arm was +1.1, +0.9, and +1.4 lines for the small, medium, and large-pupil sub-groups, respectively. The regression model–adjusted mean DCIVA consistently favored the test arm by +1.2, +1.2, and +1.4 lines in the same sub-groups.

The mean DCIVA benefit for the test arm was +0.9, +1.1, and +1.6 lines in the short, medium, and long sub-groups, respectively. The regression model–adjusted mean DCIVA consistently favored the test arm with benefits of +1.1, +1.2, and +1.6 lines in the same sub-groups.

Conclusions

The Vivinex Impress enhanced monofocal intraocular lens substantially improves intermediate vision compared to a standard aspheric monofocal IOL, regardless of pupil size and axial length, providing a strong option for patients seeking extended vision range.