Clinical Experience With A New Refractive Extended Depth Of Focus Intraocular Lens

Published 2025 - 43rd Congress of the ESCRS

Reference: PP10.13 | Type: Free paper | DOI: 10.82333/1aem-qg34

Authors: Ziqing Feng* ¹ , Chang Liu ¹ , Ruoyan Wei ¹ , Yunzhe Wang ¹ , Tianze Cui ¹ , Meiyan Li ¹ , Xingtao Zhou ¹

¹Department of Ophthalmology and Optometry, Eye &amp; ENT Hospital,Fudan University,Shanghai,China

Purpose

To evaluate the performance of the new PureSee extended depth of focus (EDF) intraocular lens (IOL).

Setting

Top clinical training hospital.

Methods

To date, 11 patients have been evaluated 3 months after cataract surgery with bilateral implantation of the PureSee (ZEN00V, DEN00V, or DETnnn; Johnson & Johnson) IOL in the capsular bag. Data collection is ongoing. Binocular uncorrected distance (UDVA), intermediate (UIVA), and near (UNVA) visual acuity were measured. Reading acuity and speed, assessed in words per minute (wpm), were evaluated using the Radner reading chart. Patient-reported outcomes were gathered using the Catquest-9SF NL, the Patient-Reported Spectacle Independence Questionnaire, and the Quality of Vision questionnaire.

Results

Mean ± SD age was 72±8 years; 82% were female. Mean SEQ was +0.14±0.28 D in the dominant and +0.05±0.20 D in the non-dominant eye. Binocular visual acuities were: UDVA -0.06±0.03 logMAR, CDVA -0.08±0.01 logMAR, UIVA +0.08±0.11 logRAD, and UNVA +0.27±0.13 logRAD. Reading speeds were 161±18 wpm (intermediate), 161±19 wpm (near), and 176±18 wpm (near with reading glasses). Reading acuity scores were: 0.14±0.05 logRAD (intermediate), 0.35±0.10 logRAD (near), and 0.20 ± 0.11 logRAD (near with reading glasses). Among participants, 73% (8/11) reported being fully spectacle-independent for distance and intermediate vision; 27% (3/11) also achieved spectacle independence for near vision. Patients reported experiencing no to minor dysphotopsias.

Conclusions

Preliminary results with the PureSee EDF IOL demonstrate excellent binocular distance and intermediate visual acuities, with functional near vision. Reading acuity was good at intermediate but limited at near without correction, showing significant improvement when using reading glasses. Patients reported high rates of complete spectacle independence for distance and intermediate vision, with minimal dysphotopsias. However, reading glasses were commonly used for near tasks.