Repeatability Of Corneal Parameters Measured By As-Oct/Placido Topographer (Cso Ms-39) In Keranatural Implanted Patients And Healthy Controls
Published 2025 - 43rd Congress of the ESCRS
Reference: PP09.11 | Type: Free paper | DOI: 10.82333/wmdf-fs58
Authors: Gabriel Santos* 1 , João Heitor Marques 2 , Beatriz Costa Vieira 3 , Diogo Rodrigues 3 , Sílvia Monteiro 3 , Ana Carolina Abreu 3 , Renato Ambrósio 4 , Pedro Menéres 2 , João Melo Beirão 2 , Pedro Manuel Baptista 2
1Neurociences,Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António,Oporto,Portugal;Neurociences,Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António,Oporto,Portugal, 2Neurociences,Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António,Oporto,Portugal;Opthalmology,Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto,Oporto,Portugal, 3Neurociences,Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António,Oporto,Portugal, 4Department of Opthalmology,3Rio de Janeiro Corneal Tomography and Biomechanics Study Group ,Rio de Janeiro, Brazil,Brazil;Department of Opthalmology,Department of Cornea and Refractive Surgery, Instituto de Olhos Renato Ambrósio,Rio de Janeiro,Brazil;Department of Opthalmology, Federal University of the State of Rio de Janeiro (UNIRIO),Rio de Janeiro,Brazil;Opthalmology,Federal University of São Paulo (UNIFESP),São Paulo, Brazil,Brazil;Opthalmology,7Brazilian Study Group of Artificial Intelligence and Corneal Analysis - BrAIN, Rio de Janeiro & Maceió,Brazil
Purpose
To evaluate the repeatability of the CSO MS-39 anterior segment optical coherence tomography (OCT) for tomographic measurements in patients following allogenic intrastromal ring segment (CAIRS)- Keranatural implantation and compare it to a healthy control group.
Setting
This study was conducted at Swiss Vision Clinic in Istanbul, Turkiye. All Keranatural patients were operated on by the same surgeon, Dr. Aylin Kilic. All measurements were performed using the CSO MS-39 AS-OCT/Placido topographer (CSO, Florence, Italy).
Methods
This study included 45 eyes of 38 patients: 23 eyes of 16 patients who underwent Keranatural implantation (mean age 31.1 ± 7.5 years, 37% male, 63% female) and 22 eyes of 22 healthy controls (mean age 28 ± 6.2 years, 59% male, 41% female). Three consecutive measurements were acquired using the AS-OCT/Placido topographer (CSO MS-39). Front and back K1, K2, Kmean, astigmatism and elevation, front Kmax, and pachymetry (central and thinnest) were evaluated. Repeatability was assessed using within-subject standard deviation (Sw), coefficient of variation (CoV), test-retest repeatability (TRT), and intra-class correlation coefficient (ICC).
Results
The CSO MS-39 demonstrated high repeatability for all corneal measurements in both Keranatural and control groups. The ICC values were consistently high (ranging from 0.867 to 0.989), indicating that the device produced very similar results each time it was used. The lowest and highest CoV values were observed in the keratoconus group, with 0.30 for K2 (steep keratometry) and 2.27 for TCT (thinnest corneal thickness), respectively. In the control group, CoV ranged from 0.35 for K1 (flat keratometry) to 2.13 for CCT (central corneal thickness). These findings suggest that while the MS-39 provides high repeatability for both groups, there is greater variability in some measurements for keratoconus eyes compared to healthy eyes.
Conclusions
The CSO MS-39 provides reliable and repeatable measurements of anterior segment parameters, including keratometry, astigmatism, pachymetry, and elevation, in patients following Keranatural implantation and in healthy controls. These consistently high repeatability and ICC values suggest that the CSO MS-39 is a valuable tool for monitoring corneal changes and stability post-Keranatural implantation.