Validity And Reliability Of Ocular Surface Evaluation Provided By A New Digital Platform In Healthy And Dry Eye Patients
Published 2025 - 43rd Congress of the ESCRS
Reference: PP09.07 | Type: Poster | DOI: 10.82333/4250-rq20
Authors: David Pablo P Pinero* 1 , Laura Barberán Bernardos 1 , Concha de la Vega 2
1Optics, Pharmacology and Anatomy,University of Alicante,Alicante,Spain, 2Optometric Clinic,University of Alicante,Alicante,Spain
Purpose
To evaluate the intrasession repeatability of ocular surface evaluations provided by a new digital platform in healthy and dry eye patients and to compare the data obtained with that provided by another diagnostic platform.
Setting
Optometric Clinic, University of Alicante, Alicante, Spain
Methods
A total of 57 eyes of 57 patients (age, 18 to 66 years) were enrolled in this study: 16 healthy eyes (control group) and 41 dry eye patients (dry eye group). A complete ophthalmological and optometric evaluation was performed in all cases. After that, three consecutive measurements were obtained with the digital platform Me-Check Pro (Espansione Group), evaluating the tear meniscus height (TMH), hyperemia level, and meibography. Likewise, a measurement of TMH was also obtained with the VX650 platform (Luneau technologies). The intraclass correlation coefficient (ICC) and the coefficient of variation (CV) were calculated to assess the level of repeatability. Agreement between devices in TMH was assessed with Bland-Altman (BA) plots.
Results
The ICC of repeated measurements was 0.543, 0.857, 0.771 and 0.919 for TMH, percentage of meibomian gland loss, meiboscale score and hyperemia score, respectively. Likewise, the CV was 15.2%, 12.6%, 8.8% and 7.7%, respectively. Significant differences (p< 0.001) were found in TMH measurements between Me-Check Pro and VX650. Specifically, in both control (Me-Check Pro 0.115±0.014 mm vs. VX650 0.153±0.032 mm, p<0.001) and dry eye groups (0.115±0.017 mm vs. 0.162±0.032 mm, p<0.001) significant differences in TMH were also found. BA plots revealed the presence of clinically relevant limits of agreement between Me-Check Pro and VX650 devices in terms of TMH measurements.
Conclusions
The digital platform evaluated provides a reliable evaluation of the ocular surface, with TMH measurements that cannot be used interchangeably with those provided by other diagnostic devices. More studies are needed to corroborate if the lower values obtained for TMH with the platform evaluated may be due to the higher level of resolution of the images of the tear meniscus obtained with it.