ESCRS - PP02.17 - Detecting Post-Laser Vision Correction Ectasia Based On Optical Coherence Tomography

Detecting Post-Laser Vision Correction Ectasia Based On Optical Coherence Tomography

Published 2025 - 43rd Congress of the ESCRS

Reference: PP02.17 | Type: Free paper | DOI: 10.82333/b7kz-fd92

Authors: Mohammed Mohammed Mahdy Tawfeek* 1 , Hanan Mohamed Abdel Hamid Ahmed 2 , Ashraf Bor'i 1 , Ahmed M. Nashaat Ali Rady 3

1Ophthalmology,Zagazig University,Zagazig,Egypt, 2Ophthalmology,General Organization Of Teaching Hospitals and Institutes (GOTHI), Mataria Teaching Hospital,Cairo,Egypt, 3Ophthalmology,Kazan Federal University,Cairo,Egypt

Purpose

To investigate changes in the epithelium and stroma in patients with post-laser vision correction (LVC) ectasia using spectral-domain optical coherence tomography (SD-OCT) and to compare these changes with those observed in post-LVC stable eyes.

Setting

An university hospital in China

Methods

Scheimpflug tomography and SD-OCT were performed on post-LVC stable and ectasia eyes. The postoperative remodeling pattern of epithelium and stroma were described. All SD-OCT machine-derived parameters were evaluated based on their receiver operating characteristic (ROC) curves, area under the curve (AUC), sensitivity, and specificity to discriminate between post-LVC stable and ectasia eyes.

Results

One hundred and eleven eyes from 111 post-LVC stable patients (41 post-TransPRK eyes, 34 post-LASIK eyes, and 36 post-SMILE eyes) and 23 eyes from 23 post-LVC ectasia patients (one post-TransPRK ectasia eye, one post-SBK ectasia eye, one post-LASEK ectasia eye, and 20 post-LASIK ectasia eyes). The unique epithelium remodeling patterns were observed in both post-LVC stable and ectasia eyes, in the latter as a "horseshoe"-like pattern. The top three ranked AUC ROC SD-OCT parameters were all derived from epithelium, including epithelium 5mm superior-inferior (cutoff value = -0.675, AUC = 0.956), epithelium 5mm inferior (cutoff value = 52.41, AUC = 0.937), and epithelium thickness range (cutoff value = -23.685, AUC = 0.936).

Conclusions

The characteristic remodeling pattern and the machine-derived SD-OCT parameters describing the epithelium remodeling of post-LVC ectasia could potentially be used for its diagnosis.