Cairs For Keratoconus: Refractive, Keratometric And High Order Aberration Outcomes
Published 2025 - 43rd Congress of the ESCRS
Reference: PP02.09 | Type: Free paper | DOI: 10.82333/ebym-1d72
Authors: Wei Wei* 1 , Jun Cai 1 , Wenjia Cao 1 , Haoxi Chen 1 , Xiyu Sun 1 , Di Shen 1
1First Affiliated Hospital of Northwestern University；Xi’an No.1 Hospital; Shaanxi Institute of Ophthalmology; Shaanxi Key Laboratory of Ophthalmology; Clinical Research center for Ophthalmology Diseases of Shaanxi Province,Xi'an,China
Purpose
To evaluate the refractive, keratometic and high order aberration outcomes after corneal allogenic intrastromal ring segment (CAIRS) implantation for keratoconus patients.
Setting
Opthalmology Excellence Center in Specialized Medical Center, Riyadh, Saudi Arabia
Methods
A pre-cut CAIRS tissues were used and implanted into a tunnel created by using the femtosecond laser. The depth of the tunnel varies between 200-300μ; the inner diameter of the tunnel ranges from 4.0 to 6.0 mm according the scotopic pupil diameter; and the outer diameter from 6.5 to 8.0 mm. Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), Cylinder (Cyl), flat and steep keratometery (K1 and K2), maximus keratometry reading (Kmax), and high order aberration (HOAs) values were recorded preoperatively and 3 to 6 months postoperatively.
Results
A total of 100 eyes of 76 patients were included in the study. Preoperative UCVA 0.10 ± 0.01 and BCVA 0.40 ± 0. 11 values improved postoperatively and reached 0.70 ± 0.05 and 0.80 ± 0.09, respectively. A statistically significant flattening of all keratometric values was observed in the postoperative period compared to preoperatively (p<0.001 for all). Average topographic astigmatism decreased from 4.5 to 2.0D. Average Kmax was 56 ± 3D preoperatively that decreased to 47 ± 2D postoperatively. In addition, high order aberration, including spherical abberation and coma values, were signficantly lower than the preoperative values at all postoperative visits (p<0.05 for all).
Conclusions
CAIRS implantation is a safe treatment option with very good visual and keratometric outcomes for suitable patients with keratoconus.