Optical Evaluations And Comparison Of Visual Disturbances Of Extended Depth Of Focus Intraocular Lenses

To do comparative assessment of the optical quality and visual disturbances (VDs) for two marketed Extended Depth of Focus (EDoF) Intraocular Lenses (IOLs).

Advanced Optical Technology (AOT) Laboratory, Alcon Research, LLC.

The optical quality of Tecnis PureSee and Clareon Vivity IOLs was assessed using Modulation Transfer Function (MTF) bench. The MTF were obtained in model eye with corneal spherical aberration of 0.2 micron for Vivity and 0.28 micron for PureSee. The halo was measured using the high dynamic range halo imaging system with and without IOL decentration. The glare type positive dysphotopsia (PD) was evaluated in a schematic model eye and using an optical bench. 

MTF measurements showed that Tecnis PureSee has similar image quality to Clareon Vivity at the distance focus. On axis halo images were comparable for both the IOLs. However, a noticeable ring structure and an asymmetric flare were observed for PureSee at 0.5 mm decentration. Glare type photic phenomenon was higher for the PureSee because of additional peripheral disk type feature of the Tecnis IOLs platform.

Both IOLs show depth of focus characteristics, but MTF for Vivity demonstrates a higher resolution from about 0.3 to 1.5 D of myopic defocus. With decentration, PureSee may exhibit halo type VD. The PD is expected to be higher for the PureSee because of smaller usable optic and a peripheral non-imaging feature. Future clinical studies can confirm the significance of these in-vitro findings.