Clinical And Patient-Reported Visual Outcomes Of A Segmental Low Power Refractive Varifocal Iol: A Prospective Study
Published 2025 - 43rd Congress of the ESCRS
Reference: PO888 | Type: Poster | DOI: 10.82333/nk00-qk42
Authors: Hao Zhang* 1 , Jorge L. Alió 1 , Ana Belén Plaza-Puche 2 , Antonio Martínez Abad 2 , Pilar Yebana 2 , Mario Cantó-Cerdán 2 , David Teren 2
1Vissum Grupo Miranza,Alicante,Spain;Division of Ophthalmology,Universidad Miguel Hernández,Alicante,Spain, 2Vissum Grupo Miranza,Alicante,Spain
Purpose
To evaluate the clinical outcomes and patient-reported visual performance following implantation of a novel segmental low power refractive varifocal intraocular lens (IOL).
Setting
Vissum (Miranza Group), Alicante, Spain
Methods
This prospective study included 25 patients (50 eyes) who underwent bilateral implantation of the Acunex Vario AN6V low power refractive varifocal IOL. Key outcomes were assessed preoperatively and at 1, 3, and 6 months postoperatively, including uncorrected and corrected distance visual acuity, intermediate and near visual acuity, manifest refraction, and slit-lamp biomicroscopy. Additional assessments included defocus curves, higher-order aberrations, contrast sensitivity, and optical quality. Patient-reported outcomes were evaluated using the Quality of Vision (QoV) and Near Activity Visual Questionnaires (NAVQ). Pre- and postoperative differences were analyzed with p < 0.05 considered statistically significant.
Results
Significant improvements were observed in UDVA, CDVA, Sphere, Cylinder, and SE (0.13±0.18, 0.03±0.06, -0.12±0.59D, -0.48±0.44D, -0.34±0.61D, p<0.05). UIVA, DCIVA, and DCNVA remained stable at 0.29±0.13, 0.28±0.16, and 0.30±0.15 logMAR postoperatively, with no significant changes at 1, 3, and 6 months. The defocus curve showed excellent distance vision (0.02±0.06 at 0.0D), declining at intermediate (-1.5D: 0.16±0.09 logMAR) and near (-2.5D: 0.31±0.11 logMAR). CS remained unchanged (p≥0.05). At 6 months, aberrrometry revealed RMS of LOA, HOA, coma, trefoil, and SA at 0.59±0.27, 0.35±0.12, 0.17±0.09, 0.23±0.12, and 0.04±0.06 μm. QoV showed minimal halos (33% never, 47% occasional). NAVQ confirmed high satisfaction in daily near-vision tasks.
Conclusions
The low power refractive varifocal IOL provides excellent spectacle independence for distance and intermediate vision while maintaining functional near visual acuity. Patients reported mild dysphotopsias, indicating good overall visual performance and tolerance.