Beyond Multifocals: Spectacle-Free Vision Using Mini-Monovision With The Lentis Comfort Edof Intraocular Lens

To evaluate the visual outcomes and spectacle independence achieved with the Lentis Comfort Extended Depth-of-Focus (EDOF) intraocular lens (IOL) in patients undergoing cataract surgery with a mini-monovision strategy. This study assesses binocular uncorrected distance visual acuity (UDVA), uncorrected near visual acuity (UNVA), and the binocular defocus curve at one-month follow-up. The goal is to determine the effectiveness of targeting plano in the dominant eye and -0.50D in the non-dominant eye in achieving functional vision across different distances while minimizing spectacle dependence and photic disturbances.

This study was conducted at Cebu Doctors University, a tertiary ophthalmology center in the Philippines, with surgeries performed by two experienced vitreoretinal surgeons. Patients underwent phacoemulsification with implantation of the Lentis Comfort EDOF IOL, following a mini-monovision targeting strategy. Postoperative visual function assessments were performed at one-month follow-up, focusing on distance, intermediate, and near visual outcomes.

This retrospective analysis included 24 eyes that underwent Lentis Comfort EDOF IOL implantation with a mini-monovision target (dominant eye plano, non-dominant eye -0.50D). Binocular UDVA and UNVA were assessed at one month postoperatively for all eyes, while a binocular defocus curve analysis was performed in a subset of 15 eyes. Descriptive statistics summarized visual outcomes, while a paired t-test evaluated pre- and post-operative differences in visual acuity. Repeated measures ANOVA assessed the trend of VA across defocus levels.

A total of 24 eyes were analyzed. At one month, 100% achieved functional near vision (UNVA 20/25 or better), confirming the mini-monovision strategy’s effectiveness in eliminating reading glasses. Binocular UDVA was 20/25 or better in 88%, with 100% achieving 20/40 or better. Defocus curve analysis (15 eyes) showed stable intermediate vision with functional near acuity at 40-50cm. No significant glare or halos were reported, contrasting with the photic disturbances seen in diffractive multifocal IOLs. These findings suggest that the Lentis Comfort EDOF IOL provides excellent spectacle independence across distances.

The Lentis Comfort EDOF IOL with a mini-monovision strategy (dominant eye plano, non-dominant eye -0.50D) provides excellent binocular distance and intermediate vision, with functional near vision and high spectacle independence. The binocular defocus curve confirms a smooth transition across vergence levels, optimizing real-world visual performance. These findings suggest that the Lentis Comfort IOL is a viable option for presbyopia correction with minimal visual disturbances. Further data collection is ongoing to strengthen these findings.