Evalutaiton The Optical Performance Of A Diffractive Intraocular Lens With An Improved Sinusoidal Profile

This study aimed to evaluate the optical performance of an extended-depth-of-focus intraocular lens (EDOF IOL) with an enhanced sinusoidal diffractive profile (SIN IOL) developed in our laboratory, and to compare its performance with that of a commercially available diffractive EDOF IOL and a refractive multifocal IOL.

Experimental evaluations were conducted at the Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology, Institute of Modern Optics, Nankai University, China.

Three IOL types were analyzed:

• Prototype SIN IOL (diffractive EDOF) with 19.15D power for distance vision 
• Tecnis Symfony ZXR00 (Johnson & Johnson, diffractive EDOF)  with a base power of 24.0 D
• Lentis Comfort LS-313 MF15 (Oculentis, refractive multifocal) with a base power of 24.0 D and an added power of 1.5 D 

      The through-focus images of the USAF-1951 resolution target were acquired under two illumination conditions: photopic (3.0 mm pupil diameter) and scotopic (4.5 mm pupil diameter), using 545 nm monochromatic light (λ = 545 nm) in a custom-designed optical bench system.

Photopic performance (3.0 mm pupil):

• 0-1.75 D defocus: Comparable to Symfony (except 1.5 D: SIN slightly lower)
• 2.0-2.5 D defocus: Superior to Symfony
• LS-313 MF15 showed optimal distance vision but inferior intermediate/near performance

Scotopic conditions (4.5 mm pupil):

• SIN IOL maintained parity with Symfony (both showing reduced vs photopic)
• LS-313 MF15 exhibited significant image quality degradation

• Equivalent through-focus performance to Symfony in both photopic and scotopic conditions
• Extended functional range surpassing Symfony at higher defocus levels
• Robust performance across pupil size variations
• No significant increase in stray light generation was observed between diffractive and refractive IOLs under the tested conditions