Comparison Between An Extended Depth Offocus (Edof) And An Enhanced Monofocalintraocular Lens

This study aimed to compare clinical outcomes and patient satisfaction among three intraocular lenses (IOLs): a monofocal IOL (Tecnis PCB00), an enhanced monofocal IOL (Tecnis Eyhance ICB00), and a non-diffractive extended depth of focus (EDOF) IOL (LuxSmart).

The study was conducted in a clinical setting involving patients who underwent bilateral cataract surgery.

A total of 132 eyes from 66 patients were randomly assigned to one of three groups corresponding to the IOL type: control (Tecnis PCB00), Eyhance (ICB00), and LuxSmart. Primary outcomes were assessed three months postoperatively, including uncorrected and best-corrected visual acuity at distance (6 m), intermediate (66 cm), and near (40 cm) vision. Monocular defocus curves from -3.50D to +1.50D were recorded under photopic conditions. Patient-reported outcomes were evaluated using the Catquest-9SF questionnaire.

All patients achieved binocular and monocular best-corrected visual acuity (CDVA) of at least 20/20, with no significant difference between groups. The mean binocular uncorrected intermediate visual acuity (UIVA) was significantly higher in the LuxSmart and Eyhance groups compared to the control (20/32 vs. 20/40, p<0.001). Uncorrected near vision was significantly better in the LuxSmart group (20/32) compared to the other groups (p=0.02). Both LuxSmart and Eyhance demonstrated a longer plateau in the defocus curve compared to the monofocal IOL.

Eyhance and LuxSmart IOLs provide superior intermediate and near vision compared to the monofocal IOL (PCB00), with LuxSmart yielding better near vision without compromising distance vision or increasing the incidence of photic phenomena. This study is the first to directly compare LuxSmart with Eyhance in a real-world setting, supporting existing literature on the efficacy of these advanced IOL designs.