Sd-Oct Analysis Of Palisades Of Vogt In Limbal Stem Cell Deficiency: A Comparative Study With Normal Eyes

Published 2025 - 43rd Congress of the ESCRS

Reference: PO790 | Type: Poster | DOI: 10.82333/vn85-6t14

Authors: Anjana Karunakaran* ¹

¹Ophthalmology,Medeor Hospital,Dubai,United Arab Emirates

Purpose

This study aimed to investigate the morphology of Palisades of Vogt (POV) in normal eyes and in patients with limbal stem cell deficiency (LSCD) using spectral domain optical coherence tomography (SD-OCT).

Setting

This study was conducted in a tertiery care ophthalmological setting.

Methods

The study included 10 normal subjects (5 males, 5 females) and 5 patients with LSCD. SD-OCT imaging was performed on the superior and inferior limbal regions. The images were analyzed to calculate:

1. *Palisade Ridge Height (PRH)*: Calculated for three zones in both the superior and inferior limbus.

2. *Interpalisade Epithelial Rete Peg Distance (IRP)*: Calculated for the three zones in both the superior and inferior limbus.

Results

The study found:

1. *Normal Eyes*: Mean PRH values for the superior zone were 80.90 μm, 83.90 μm, and 81 μm for zones a, b, and c, respectively. Mean IRP values were also calculated.

2. *LSCD Patients*: Morphological characteristics of POV were described in detail.

Conclusions

The study concluded that in vivo SD-OCT imaging is a safe, contactless modality for assessing POV morphology. The findings provide valuable information for understanding limbal stem cell function and planning ocular surface reconstruction, improving diagnosis and treatment of LSCD and other ocular surface disorders.