Relationship Between Segmental Ocular Biometry And Refractive Status In Myopic Eyes

The purpose of the present study is to correlate biometric and refractive parameters in myopic patients.

Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António.

This is a large scale coss-sectional study.

Biometric data from Axial Length (AL), Spur-to-spur distance (S-T-S)and segmental lengths - Central Corneal Thickness (CCT), Anterior Chamber Depth (ACD) and Lens Thickness (LT) - were assessed by means of swept-source OCT with the ANTERION®. The variable Vitreous Cavity Length was built [VCL = AL – (CCT + ACD + LT)]. Ratios between VCL and AL (R_VCL/AL) and between STS and AL (R_STS/AL) were calculated.

Objective refractive status - Sphere (S), Cilinder (C) and Spherical Equivalent (SE) - was assessed through the KR-800 Auto Kerato-Refractometer®.

Correlations (Pearson coefficient) were addressed between ocular biometric parameters and refractive status.

The present study included 786 eyes from 393 individuals, with a mean age at baseline of 31.4 (±6.4) years old.

Correlations were found in the following variables:

- Spherical equivalent: AL [mm] (-0.523, p <0.001), VCL [mm] (-0.399, p <0.001), R_VCL/AL (-0.379, p <0.001) and R_STS/AL (-0.539, p <0.001)

- Axial length: STS [mm] (0.333, p <0.001), VCL [mm] (-0.979, p <0.001), R_VCL/AL (0.784, p <0.001) and R_STS/AL (-0.844, p <0.001)

- Vitreous Cavity Length: AL [mm] (-0.979, p <0.001), STS [mm] (0.237, <0.001), R_VCL/AL (0.893, p <0.001) and R_STS/AL (-0.848, p <0.001)

The present study found multiple correlations in refractive and biometric parameters. The data presented highlights the potential role of the incorporation of segmental and transversal biometric parameters in the study of myopic eye.