A New Formula Jl1 For Optimizing The Selection Of Implantable Collamer Lens Which Is Based On The Measurement Of Ciliary Sulcus-To-Sulcus Distance Using Ultrasound Biomicroscopy
Published 2025 - 43rd Congress of the ESCRS
Reference: PO750 | Type: Free paper | DOI: 10.82333/q41b-hk45
Authors: Oege Goslings* 1 , Olga Van der Put 1 , Daniel Cheng 2
1Ophthalmology,ElisabethTweeSteden Hospital,Tilburg,Netherlands, 2MedTech,Johnson and Johnson,Irvine,United States
Purpose
To identify the anterior segment parameters related to vault at 1 month postoperatively, and establish a predictive formula for Implantable Collamer Lens (ICL) model selection based on ciliary sulcus-to-sulcus distance.
Setting
Bidirectional study. In the formula - development group, a total of 114 eyes from 57 subjects (16 males and 41 females) were included aged 18-49 years (25.79±7.46). In the formula - validation group, there were 33 eyes from 18 subjects (5 males and 13 females) aged 18 - 41 years (26.67±7.87).
Methods
Standardized preoperative assessments included: uncorrected visual acuity, best-corrected visual acuity, biometry (IOL Master: WTW, AL, LT; Pentacam: Kf, Ks, ACD, ACV, ACA), and ultrasound biomicroscopy (H/V STS). ICL implantation followed STAAR Nomogram. Vault measurements were obtained via anterior segment optical coherence tomography at 1-month postoperative. The correlation between the vault and each preoperative parameter was calculated. Multivariable regression identified vault predictors. The validation group used mean absolute error (MAE), root mean square error (RMSE), and Bland-Altman plots to assess the accuracy of the prediction formula.
Results
Significant vault determinants included: corneal refractive power in the flat meridian, corneal refractive power in the steep meridian, horizontal corneal diameter, axial length, horizontal/vertical sulcus-to-sulcus distancesand, phakic intraocular lens size (P < 0.001). The final regression model JL1 :Vault (μm) = 633.0 + 1281.4 × (ICL size) - 1385.8 × HSTS (R² = 0.983, adjusted R² = 0.979). Validation showed MAE=127.1 μm and RMSE=150.3 μm. The Bland-Altman plot demonstrated that the majority of the scatter points were essentially within the range of the 95% confidence interval.
Conclusions
根据睫状沟到睫状沟距离选择的 ICL 显示出较高比例的安全术后穹窿。然而，临床医生应考虑针对解剖极端情况进行模型调整：水平角膜直径≤ 11.2 mm，前房深度≤ 3.1 mm，前房体积≤ 150 mm³，或轴向长度≤ 24.0 mm。