Characteristic Of Macular Structure And Microvascular System In Patients Undergoing Evo Icl Implantation Using Ultra Widefield Swept-Source Optical Coherence Tomographic Angiography
Published 2025 - 43rd Congress of the ESCRS
Reference: PO739 | Type: Free paper | DOI: 10.82333/q1ve-e586
Authors: Karl Mercieca* 1 , David Lubeck 2 , Keith Barton 3 , Nathan Kerr 4 , Shamil Patel 5
1University of Bonn Eye Clinic,Bonn,Germany, 2Arbor Centers for EyeCare,Homewood, IL,United States, 3Moorfields Eye Hospital,London,United Kingdom, 4Centre for Eye Research Australia,East Melbourne,Australia, 5Eye Physicians and Surgeons of Arizona,Scottsdale, AZ,United States
Purpose
To quantitively evaluate the characteristic of macular structure and microvascular system in patients with myopia before and after EVO ICL implantation using Ultra widefield Swept-Source Optical Coherence Tomographic Angiography (SS-OCTA).
Setting
Prospective study. The study was in accordance with the tenets of the Declaration of Helsinki and was approved by the Ethics Committee of the Eye and ENT Hospital of Fudan University. Written informed consent was acquired from all patients. A total of 107 eyes from 55 patients who met the indications for EVO ICL surgery were recruited from January to June 2021.
Methods
Prospective study. A total of 107 eyes from 55 patients who met the indications for EVO ICL surgery were recruited from January to June 2021. All patients underwent a comprehensive ocular examination. SS-OCTA was employed to ascertain the macular morphology and microvascular system, including retinal thickness (RT), retinal nerve fiber layer thickness (RNFLT), choroidal thickness (CT), deep vascular complexes (DVC), superficial vascular complexes (SVC), choroidal vessel volume (CVV), choroidal stromal volume (CSV) and choroidal vascular index (CVI). The correlations between these variables and demographic information were further analyzed.
Results
The safety and efficacy indices of EVO ICL implantation were 1.09±0.16 and 1.03±0.17, respectively. RT was thicker in the superior and temporal quadrant, while no significant change in all orientations after surgery was found. Significant spatial differences in RT and RNFLT was observed, and both tended to be thinner postoperatively. In terms of microvascular indices, choroidal-related parameters thinned only in the inferior quadrant of the outer ring 9-21 mm, whereas the SVC thinned significantly in all directions postoperatively. Correlation analysis showed that RT, RNFLT and SVC were positively correlated. Multiple regression showed that CVV in 0-1mm and SVC in 1-3mm were the two variables significantly correlated with axial length (AL).
Conclusions
ICL surgery has no significant effect on the choroidal layer, but causes changes in the superficial retinal layer. In patients with high myopia and long AL, superficial retinal and choroidal microvascular changes in the center of macular region should be focused.