Anatomical Differences Between Left And Right Eyes In Anterior Chamber Parameters Under Different Orientations In Myopic Groups Assessed By Ubm

To investigate the anatomical differences in anterior chamber parameters in myopic patients by right and left eye groups in various orientations.

Eye & ENT Hospital.

A cross-sectional study. A total of 46 patients with different degrees of myopia were recruited. Every patient's anterior chamber parameter in different orientations were measured by ultrasound biomicroscope (UBM), including sulcus to sulcus (STS), distance from anterior surface of crystalline lens to STS (STSL), anterior segment length (ASL), and anterior chamber depth (ACD). The orientations were divided into 6 orientations averagely. Differences in the anterior chamber parameters between the patients' left and right eyes in different orientations were symmetrically compared and further analysis for correlation, and the anterior chamber parameters of the eyes were performed.

All patients were matched for baseline parameters in the right and left eyes. STS had significant interocular differences in nasal-superior meridian, showing smaller values in the right eyes (P=0.017). Other parameters, including STSL, ASL and ACD had no discrepancy (all P>0.05). Correlation analysis showed that STS was significantly correlated with axial length (AL), keratometry of the front and back cornea (Kf and Kb). Multiple regression revealed a significant positive correlation between STS and Kb.

The anterior segments of myopia patients had good binocular mirror symmetry effects, while the two eye differences mainly concentrated in the superior-nasal region of the STS.