The Relationship Between High-Order Aberrations Of Anterior Corneal Surface And Age In Patients With Low And Moderate Myopia Correlation Degree And Clinical Significance
Published 2025 - 43rd Congress of the ESCRS
Reference: PO697 | Type: Free paper | DOI: 10.82333/y0gk-1q33
Authors: Xiaosong Han* 1 , Fei Xia 1 , Xiaoyu Zhang 1 , Zhe Zhang 1 , Meng Li 1 , Jing Zhao 1 , Xingtao Zhou 1
1Ophthalmology,Fudan Eye & ENT Hospital,Shanghai,China
Purpose
To observe the difference of high-order aberrations of the anterior surface of cornea in patients with low and moderate myopia at different ages。
Setting
To provide evidence for the study of visual quality and personalized corneal refractive surgery.
Methods
A total of 220 patients with low and moderate myopia in this study were divided into three groups according to their age. Group A was younger than or equal to 20 years old (80 people, 160 eyes); Group B, 20 to 40 years old (80 people, 160 eyes); Group C is more than or equal to 40 years old (60 people, 120 eyes).The Pentacam anterior segment analyzer of OCULUS, Germany, was used to complete multiple examinations, and the Zernike aberration analysis software was used to analyze the range of 6 mm in the center of the cornea. The average value of the data with more than three times of qualified detection quality was taken, and the higher-order aberration C7, C8, C12, and RMS-HOA data were recorded
Results
With the increase of age, the higher-order aberrations of the anterior surface of the cornea increased in varying degrees. Age was positively correlated with the higher-order aberrations, of which C7 and RMS-HOA were the most obvious. The C7 on the anterior surface of cornea in groups A, B and C were 0.08 ± 0.04, 0.11 ± 0.06, 0.14 ± 0.09, respectively; C8 is 0.05 ± 0.05,0.07 ± 0.05,0.06 ± 0.07 respectively; C12 on the anterior surface of cornea was 0.17 ± 0.07,0.18 ± 0.06,0.20 ± 0.09, respectively; The RMS-HOA of the anterior surface of cornea was 0.26 ± 0.11,0.31 ± 0.14,0.37 ± 0.018, respectively.
Conclusions
In patients with low and moderate myopia, the higher order aberrations of the anterior surface of the cornea increase with age, and the vertical coma is the most obvious. The effect of the increase of higher-order aberrations on the visual function of the whole eye and whether it can be corrected by personalized corneal refractive surgery need further study and observation.