ESCRS - PO654 - Aggregate And Comparative Results Of Ab Externo Implantation Of Twodifferent Gel Stent Models Performed At The Slit Lamp (Slx)

Aggregate And Comparative Results Of Ab Externo Implantation Of Twodifferent Gel Stent Models Performed At The Slit Lamp (Slx)

Published 2025 - 43rd Congress of the ESCRS

Reference: PO654 | Type: Free paper | DOI: 10.82333/x0w9-pb24

Authors: Youngsub Eom* 1 , Kyungmin Koh 2 , Hungwon Tchah 2 , Joo Young Shin 3 , Jong Jin Jung 2 , Young Kook Kim 4 , Sohee Jeon 5 , Hyoung Won Bae 6 , Dong Hyun Kim 1

1Korea University College of Medicine,Seoul,Korea, Republic Of, 2Kim's Eye Hospital, Konyang University College of Medicine,Seoul,Korea, Republic Of, 3Seoul Metropolitan Government Seoul National University Boramae Medical Center,Seoul,Korea, Republic Of, 4Seoul National University College of Medicine,Seoul,Korea, Republic Of, 5Keye Eye Center,Seoul,Korea, Republic Of, 6Severance Eye Hospital, Yonsei University College of Medicine,Seoul,Korea, Republic Of

Purpose

The purpose of this study is to report the aggregate and comparative outcomes of the Xen 45 and the Xen 63 gel stents implanted using a novel ab externo technique at the slit lamp.

Setting

Private ophthalmology clinic

Methods

Patients suffering from uncontrolled glaucoma despite maximal medical therapy were selected to undergo the Xen implantation procedure. The surgeon performed an ab externo Xen implantation technique with mitomycin C at the slit lamp under topical anesthesia. One of the two groups of patients received the Xen 45 and the other group received the Xen 63 implant. The preoperative and postoperative data from these patients were collected retrospectively. The data was analyzed to compare preoperative and postoperative intraocular pressure control, number of medications, mean deviation on the visual field test, and other pertinent data points. The postoperative outcomes of the two groups were compared using a Student’s t-test.

Results

24 consecutive eyes of 22 patients were included in the statistical analysis. The patients had a mean age of 68.08. The IOP was significantly reduced from a preoperative mean of 20.95 mmHg to a post-operative mean of 11.82 mmHg at the 3-month postoperative visit (p<0.05). The number of medications used was also significantly reduced from a mean of 3.8 down to a mean of 1.05 (p<0.05). When comparing the two groups, there was no statistically significant difference in postop IOP between the eyes that received the Xen 45 and those with the Xen 63, except at the first postop week. The procedure was very well tolerated by the subjects in both groups. Hypotony was common in the first two postop weeks but resolved spontaneously in most cases.

Conclusions

SLX is an effective Xen placement technique which can be performed in the office with no special equipment. The results are comparable to the conventional ab interno and ab externo implantation techniques performed in the operating room. We did not find any significant difference between the outcomes of the Xen 45 and the Xen 63.