Clear Cornea Post Sever Chemical Burn Without Keratoplasty (5 Years Study)

To show that the effect of using  auto graft limbal stem cell and amniotic membrane and auto serum eye drops to reach clear cornea post sever chemical burn without the  need to do keratoplasty 

The MIOR

 Prospective interventional study of (10) eyes of 10 patients  with unilateral chemical burn . follow up period ranges from 6 m -1y.Inclusion Criteria :  unilateral chemical burn .Excluison Criteria :  bilateral chemical burn. Surgical Technique :  , I excised the adhesions and  fibrous tissue on the surface of the cornea , prepare the stem cells from other eye from superior part of normal cornea and divided it into 2 equal pieces , move them to the other eye ,suturing them at the sides of the cornea , fashion a large layer of the fresh amniotic membrane that cover the cornea and  sclera , suture the amniotic to the sclera ,  suture the residual parts of conjunctiva above the amniotic to keep the amniotic membrane in place for long time .

PreOperative :full ophthalmic examination specially visual acuity , anterior seg OCT , U/S .post operative:  signs of improvement as decrease corneal vascularization, clarity of cornea ,UCVA, BCVA, pentacam, Autoserum eye drops .

results :60% of eyes treated with auto graft limbal stem cell , amniotic membrane and auto serum eye drops  reach clear cornea post sever chemical burn without the  need to do keratoplasty and this take from 9 months -1 year . 

 Chemical burn to the eye usually have a very poor prognosis

Limbal stem cell transplantation is the only hope for those patient who have massive destruction of their original stem cells

Use the amniotic membranes  and auto serum eyedrops  help the healing of these cases and some times give unexpected marvelous results that the corneas become almost clear and  we donot need to do keratoplasty but this need long time