Give The Vision Another Chance
Published 2025 - 43rd Congress of the ESCRS
Reference: PO636 | Type: Free paper | DOI: 10.82333/ss2p-h239
Authors: Giulia Coco* 1 , Giuseppe Spera 1 , Giacomo Ambrosini 1 , Gianluca Manni 2
1Department of Clinical Sciences and Translational Medicine,University of Rome Tor Vergata,Rome,Italy, 2Department of Clinical Sciences and Translational Medicine,University of Rome Tor Vergata,Rome,Italy;IRCCS-Fondazione Bietti,Rome,Italy
Purpose
To discuss management of a child with conjunctivalization & corneal vascularization after severe trauma destroyed a large area of Limbal stem cell
Setting
Single center
Methods
10 Years old Child with UCVA 0.05 underwent Limbal Stem Cell Autograft.
After corneal pannus dissection, the patients underwent Limbal stem cell autograft where limbal biopsy was harvested from the contralateral eye. Followed by applying of amniotic membrane. The primary outcome measure was anatomical success in the form of restoration of a completely epithelised, stable and avascular corneal surface
Results
No intraoperative complications were encountered, and no adverse reactions developed in donor eyes. Impression cytology in selected cases showed restoration of the corneal epithelial phenotype and regression of goblet cells from the recipient cornea.
The patient UCVA become 0.5 & his BCVA 0.7
Conclusions
Limbal autograft transplantation is recommended for treatment of widespread ocular surface damage with loss of limbal epithelial stem cells
It is a safe and effective method for restoring the corneal epithelium