ESCRS - PO564 - Contralateral-Eye Analysis Of Deep Anterior Lamellar Keratoplasty Versus Mushroom Penetrating Keratoplasty Over 5 Years

Contralateral-Eye Analysis Of Deep Anterior Lamellar Keratoplasty Versus Mushroom Penetrating Keratoplasty Over 5 Years

Published 2025 - 43rd Congress of the ESCRS

Reference: PO564 | Type: Free paper | DOI: 10.82333/bzvy-5s14

Authors: Alexander II Lanzuela Gonzales* 1 , Jorge Alió Del Barrio 2 , Hao Zhang 2 , Mario Cantó-Cerdán 3 , Antonio Martínez Abad 3 , Pilar Yebana 3

1Department of Ophthalmology,Ospital ng Makati,Makati,Philippines;Department of Cornea and Refractive Surgery,Shinagawa Lasik and Aesthetics Center,Taguig,Philippines;Cornea, Cataract and Refractive Surgery Unit,Vissum Grupo Miranza,Alicante,Spain, 2Cornea, Cataract and Refractive Surgery Unit,Vissum Grupo Miranza,Alicante,Spain;Division of Ophthalmology, School of Medicine,Universidad Miguel Hernández,Alicante,Spain, 3Cornea, Cataract and Refractive Surgery Unit,Vissum Grupo Miranza,Alicante,Spain

Purpose

To compare the clinical outcomes of patients who received deep anterior lamellar keratoplasty (DALK) in one eye and mushroom penetrating keratoplasty (MK) in the fellow eye.

Setting

Patients underwent keratoplasty at the department of ophthalmology of “Villa Igea”, Ospedali Privati Forlì (Forlì, Italy) between July 2006 and December 2023.

Methods

This is a retrospective review of prospectively collected data. The main indication for keratoplasty was keratoconus (75.0%). Primary outcomes were best spectacle-corrected visual acuity (BSCVA), refractive spherical equivalent (SE), and topographic cylinder (TC). Kaplan-Meier curves were drawn for both DALK and MK to compare the cumulative probability of obtaining a BSCVA ≤0.3 LogMAR until the end of the follow-up.

Results

We included 62 patients, who underwent DALK in one eye and MK in the fellow eye. Mean follow-up was 2.9±2.2 years (up to 10 years). One year after surgery, BSCVA was significantly better in the DALK group (0.10±0.11 vs 0.16±0.18 LogMAR, P=0.006); however, no significant differences between the 2 groups were observed at later follow-up times. BSCVA values at the last available follow-up examination were 0.09±0.12 and 0.11±0.15 LogMAR, respectively for DALK and MK (P=0.53). The probability of retaining a BSCVA <0.3 LogMAR at 5 years was 84.8% and 82.8%, respectively for DALK and MK (P=0.85). Final TC was 4.39±2.87 D for DALK and 4.20±2.12 D for MK (P=0.92). Final SE was -1.26±3.35 D for DALK and -1.58±2.49 D for MK (P=0.62).

Conclusions

This study allowed for direct intra-patient evaluation of DALK and MK. Our findings showed faster visual recovery for DALK 1 year after surgery, but no significant differences at later postoperative times for BSCVA, refractive SE, and TC.