A Comparative Study Of Combined Versus Staged Dsaek And Phacoemulsification In Patients Of Fuchs’ Endothelial Corneal Dystrophy With Cataract
Published 2025 - 43rd Congress of the ESCRS
Reference: PO535 | Type: Free paper | DOI: 10.82333/ntaw-9x47
Authors: Richard Mcneely 1 , Jonathan Moore* 2 , Niraj Mandal 1 , Stephen Stewart 1
1Cathedral Eye Clinic,Belfast,United Kingdom, 2Cathedral Eye Clinic,Belfast,United Kingdom;Aston University,Birmingham,United Kingdom;Queens University Belfast,Belfast,United Kingdom;Tianjin Medical University ,Tianjin,China
Purpose
To compare the outcomes of staged versus combined DSAEK and phacoemulsification in patients of FECD with cataract.
Setting
This was a prospective cohort study done at Dr. R. P. Centre for Ophthalmic
Sciences, AIIMS, New Delhi.
Methods
Forty patients of FECD with cataract were divided into two groups; 20 patients underwent phacoemulsification with PCIOL followed by DSAEK procedure after 2 months (group 1), while 20 patients underwent phacoemulsification with PCIOL and DSAEK procedure in the same sitting (group 2).
Results
The mean log MAR BSCVA at 6 months in group 1 was 0.315 ± 0.13 and in
group 2 was 0.321 ± 0.10 (p = 0.87). The mean CCT at 6 months in group 1 was
543.05 ± 34.15 microns and in group 2 was 574.65 ± 51.61 microns (p = 0.02). The
mean ECD at 6 months in group 1 was 2016.05 ± 66.80 cells/mm2 and in group 2 was
1773.65 ± 84.48 cells/mm2 (p<0.001). The mean endothelial cell loss at 6 months in
group 1 was 28.48 % and in group 2 was 35.52 % (p<0.001). Graft dislocation
occurred in 2 patients (10%) in group 1 and 5 patients (25%) in group 2 (p<0.001).
Graft rejection/graft failure did not occur in any patient in both groups (p = 0.99).
Conclusions
In patients of FECD with cataract, staged DSAEK and phacoemulsification
leads to lesser endothelial cell loss, rebubbling rate and CCT as compared to combined DSAEK and phacoemulsification.