Comparative Results Of Two Hydrophobic Preloaded Iols Implantation In Patients With High Myopia
Published 2025 - 43rd Congress of the ESCRS
Reference: PO392 | Type: Free paper | DOI: 10.82333/9s6g-eb34
Authors: Verena Anna Englmaier* 1 , Pascal Rohde 2 , Leo-Lion Eisfeld 1 , Nicole Eter 1 , Gunther Joos 2 , Lamis Baydoun 3
1Ophthalmology,University Hospital Münster,Münster,Germany, 2Anesthesiology,University Hospital Münster,Münster,Germany, 3Ophthalmology,University Hospital Münster,Münster,Germany;ELZA Institute,Dietikon/Zurich,Switzerland;Oogcentrum Eibergen,Eibergen,Netherlands
Purpose
To compare the capsular and axial stability of two monofocal hydrophobic IOL platforms (Alcon Clareon and Hoya iSert 251) during 6 months of follow-up after cataract surgery in patients with axial length exceeding 26 mm. This was IIT #68009797 supported by a grant from Alcon.
Setting
UCLA Department of Ophthalmology, Stein Eye Institute, Los Angeles, USA
S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, Russia
Methods
Eighty-six highly myopes (86 eyes), underwent phacoemulsification and IOL implantation. Patients were randomly selected to receive implantation of the two IOLs only in one eye. 40 eyes implanted with Clareon, and 46 eyes implanted with iSert 251. All patients were examined in 1st day, 1 week, 1, 3, and 6 months after the surgical procedure. UCVA and BCVA were assessed monocularly using a CV-5000 phoropter with an ACP-8 chart projector. Anterior segment OCT was performed (CASIA2) to determine the axial position of the IOL. IOL rotation was measured using the “Axis Assistant” smartphone application. IOL axis was defined as the line connecting the centers of the two haptic elements.
Results
No statistically significant differences were found between groups for IOL tilt and decentration.T he mean IOL tilt at 6 m after surgery was 4.49°±1.52 in Clareon group, and 4.57°±1.83 in iSert group. The mean IOL decentration 6 months after surgery was 0.27±0.16mm in Clareon group, and 0.31±0.20 mm in iSert group. Maximal values and numbers of patients with tilt over 5° were higher in iSert group. There were no eyes with clinically significant IOL decentration in both groups. Аn absolute value of axial displacement was relatively small (median 0.1 mm in both groups, p>0.05). The IOL axis position after 1 and 6 months in Clareon and iSert groups were: -2.7±15.1° and -2.9±24.7° (p>0.05).
Conclusions
This study supports the long-term stability of both IOL platforms in patients with an axial length exceeding 26 mm. Clareon injection system provided better corneal wound safety with less corneal edema and local endothelial damage on the 1st day after surgery.