Role Of Capsular Tension Ring, Polishing, And Biomarkers In Capsular Phimosis Associated With Retinitis Pigmentosa
Published 2025 - 43rd Congress of the ESCRS
Reference: PO297 | Type: Free paper | DOI: 10.82333/jejy-pv81
Authors: Avinoam Shye* 1 , Aya Wattad 1 , Igor Kaiserman 2 , Gur Munzer 3 , Tzachi Sela 3 , Michael Mimouni 4 , Eyal Cohen 5
1Ophthalmology,Tel Aviv Sourasky Medical Center,Tel Aviv,Israel, 2Ophthalmology,Barzilai Medical Center,Ashkelon,Israel;Care-Vision Laser Center,Tel Aviv,Israel;Faculty of Health Sciences,Ben-Gurion University of the Negev,Beer Sheba,Israel, 3Care-Vision Laser Center,Tel Aviv,Israel, 4Ophthalmology,Rambam Health Care Campus,Haifa,Israel;Ruth and Bruce Rappaport Faculty of Medicine,Technion - Israel Institute of Technology,Haifa,Israel, 5Ophthalmology,Tel Aviv Sourasky Medical Center,Tel Aviv,Israel;Care-Vision Laser Center,Tel Aviv,Israel;Faculty of Medicine,Tel Aviv University,Tel Aviv,Israel
Purpose
Increased sub-clinical inflammation in Retinitis Pigmentosa may accelerate capsular phimosis. We aimed to evaluate the role of Capsular Tension Ring (CTR) implantation with anterior capsular polishing in preventing this, alongside assessing intraocular inflammation biomarkers
Setting
A Prospective Interventional study with Retinitis Pigmentosa at tertiary eye care centre, India
Methods
20 patients (40 eyes) with Retinitis Pigmentosa were included & both eyes were operated. CTR implantation & anterior capsular polishing was done in one eye & other was control. Patients were evaluated pre-op & periodically in the post-op period for 6 months where incidence of capsular phimosis was assessed. Tears & aqueous were collected & assessed for inflammation using a novel biomarker kit.
Results
CTR with capsular polishing showed significantly reduced rates of capsular phimosis post-operatively with better visual outcomes & lesser decentration & tilt. Biomarker levels for inflammation were also significantly raised in both groups with specific increase in IL-1 and MMP9 levels.
Conclusions
CTR with capsular polishing proves to be an easier technique which prevents capsular phimosis leading to better post operative outcomes. Biomarker analysis shows it is prudent to keep the patient on a longer course of steroids or on a safer & effective targeted therapy.
Financial Disclosure- None