ESCRS - PO250 - Corneal And Epithelial Thickness Measurements: Agreement Of Two Different Ocular Coherence Tomography Devices

Corneal And Epithelial Thickness Measurements: Agreement Of Two Different Ocular Coherence Tomography Devices

Published 2025 - 43rd Congress of the ESCRS

Reference: PO250 | Type: Free paper | DOI: 10.82333/bxce-da42

Authors: Bruno Guerreiro Dias* 1 , Rafael Whitfield 1 , Inês Leal 1 , Luís Abegão Pinto 1

1Ophthalmology,Hospital de Santa Maria,Lisbon,Portugal

Purpose

To compare the epithelial and pachymetric thickness-based parameters of two different Fourier-domain optical coherence tomography (OCT) devices and to find out whether they can be used interchangeably.

Setting

Zentrum für Refraktive Chirurgie, Augenzentrum am St. Franziskus Hospital

Methods

24 normal eyes and 32 eyes post keratorefractive lenticule extraction(KLEx) at least 1 month ago that had corneal thickness and epithelial thickness maps with Cirrus 5000 and Avanti RTVue 100 were evaluated. The following parameters of the two OCT devices were examined: minimum corneal thickness(Pachy min), minimum corneal thickness minus the median corneal thickness(Pachy min-med), average corneal thickness of the superonasal octant minus the average corneal thickness of the inferotemporal octant(Pachy SN-IT), average corneal thickness of the superior octant minus the average corneal thickness of the inferior octant(Pachy S-I), minimum epithelial thickness(Epi min) and maximum epithelial thickness(Epi max).

Results

Pachy min and Epi max measurements had a good agreement within the two devices (ICC was 0.906 and 0.839, respectively). In the normal subject group, there was a significant correlation between two devices in Pachy min (p=0.040), Pachy min-med (p=0.033), and Epi max (p<0.001). In the post-KLEx group, only Pachy min and Epi max measurements (p<0.001 for both) had a significant correlation between the two devices.

Conclusions

Anterior segment OCT is a valuable method to evaluate corneal and epithelial thickness measurements. However, the measurements between the two OCTs in this study differed significantly. Therefore, they may not be used interchangeably.