A Study To Assess Clinical Performance And Visual Outcomes Of Klex Using The Ziemer Femto Ldv Z8 Platform (Clear)

To assess the clinical performance and visual outcomes of KLEX  Using the Ziemer FEMTO LDV Z8 Platform (CLEAR)

Nethradhama Super Speciality Eye Hospital, Bangalore

A prospective, randomized study wherein 78 eyes undergoing keratorefractive intrastromal lenticule surgery in the form of CLEAR were evaluated preoperatively, intraoperatively as well as postoperatively on days 1, 15 and 90. End outcomes included spherical equivalent refractive accuracy, spherical equivalent refractive efficacy and comparison of attempted versus achieved spherical equivalent refraction. Prior to surgery, all patients underwent a complete ophthalmic evaluation, including manifest refraction, slit-lamp bio microscopy, non-contact tonometry and dilated fundus examination. The refractive target for all eyes was emmetropia. Objective Scatter Index (OSI) was measured usgin HD- Analyser at all visits.

It was found that uncorrected distance visual acuity (UDVA) and spherical equivalence had improved significantly by postoperative day 90 (p< 0.001). OSI values also improved steadily from postoperative day 1 to day 15 and 90. Initial outcomes of CLEAR showed excellent efficacy and accuracy with respect to postoperative spherical equivalence outcomes. Most patients (n=99%) had postoperative astigmatism of 0.25D or less. CLEAR also showed excellent results in the treatment of moderate to high astigmatism. 

Initial outcomes of CLEAR using the Zeimer platform has shown favourable results making it a good choice for minimally invasive keratorefractive procedures for the treatment of mild to moderate and even higher grades of myopic astigmatism. Longer follow up periods will be required in future studies.