Influence Of Preservatives And Dose-Format In Adherence To Glaucoma Medications In A Wide Population
Published 2025 - 43rd Congress of the ESCRS
Reference: PO1003 | Type: Poster | DOI: 10.82333/zbj3-sn49
Authors: Ignacio Pereira-Gonzalez* 1 , Javier Benitez-del-castillo Sanchez 2 , Juan Antonio Cordoba Doña 2 , Soledad Jimenez Carmona 3
1H.U. Juan Ramon Jimenez,Huelva,Spain, 2U.H. Jerez,Jerez,Spain, 3H.U. Puerta del mar,Cadiz,Spain
Purpose
To analyze the influence of preservatives and dose-format in adherence to glaucoma medications.
Setting
Observational retrospective study of patients
Methods
Observational retrospective study of patients (N1602) perceiving glaucoma medications (minimum treatment time of six months). Medication possession ratio (MPR), extracted from claims data and defined as the number of months which complete prescription supply is collected from the pharmacy divided by the number of months between the first prescription and the last study visit.
Is related in a univariate model with the presence of preservatives (U Mann Whitney) and the uni or multi-dose format (U Mann Whitney). P< 0.05 is considered statistically significant.
Results
Patients with prescriptions without preservatives have obtained a mean MPR of 72.38 while patients with prescriptions with preservatives have obtained a mean MPR of 66.16. All this with a statistical significance of P less than 0.05 (0.034).
Patients with uni-dose eyedrops have obtained a mean MPR of 71.32 while patients with multi-dose eyedrops have obtained a mean MPR of 67.17. All this with a statistical significance of P greater than 0.05 (0.14)
Conclusions
Patients whit prescriptions without preservatives have shown to have more adherence to topical antiglaucoma medication. No difference was found according to dose format.