Clinical Outcomes Of A Novel Full Range Of Vision Intraocular Lens At 6- And 12-Months After Bilateral Implantation

To evaluate the visual outcomes of the new refractive Full Range of Vision intraocular lens (IOL), LuxLife, in bilateral cataract surgery patients at 6 and 12 months. This study assesses its performance across distance, intermediate, and near visual acuity, refractive error, depth of field, and quality of life. Additionally, it investigates the lens’s suitability for toric applications, assessing 6-months rotational stability and centration, aiming to establish LuxLife as a reliable solution for full-range vision post-surgery.

Seven clinical centres in Spain and Czech Republic.

A multicenter, prospective, non-randomized, open-label study that included cataract patients, aged 50 years or older with no ocular comorbidity, and maximum preoperative corneal astigmatism of 1.0 D. Clinical endpoints include manifest refraction spherical equivalent (MRSE), corrected distance visual acuity (CDVA), uncorrected and distance corrected intermediate visual acuity at 66 cm (UIVA and DCIVA), uncorrected and distance corrected near visual acuity at 40 cm (UNVA and DCNVA), and binocular defocus curve, rotational stability and centration, dysphotopsia and quality of Life using the CatQuest. Patients were followed up for 11–13 months.

114 patients(age:68±6.9) were bilaterally implanted with the lens. At 6- and 12-M the MRSE was -0.13±0.44 and -0.11±0.40 D and binocular UDVA was 0.07±0.1 and 0.08±0.12, UIVA was 0.05±0.1 and 0.06±0.13 and UNVA was 0.06±0.09 and 0.07±0.10 logMAR, respectively. 6M binocular defocus curve at a threshold of 0.2 logMAR of CDVA shows a continuous depth of field exceeding 3.0D. At 6M, the lens demonstrated showed an absolute rotational stability of 3.13±3.54 degrees and absolute decentration pupil of 0.23±0.15 mm from surgery. Patients reported no to some difficulties in their everyday life (90% vs 49%), and especially in reading newspapers (99% vs 40%) and reading price tags while shopping (99% vs 53%), at 6M and preoperatively respectively.

The new refractive Full Range of Vision IOL, LuxLife, demonstrated promising clinical outcomes in bilateral cataract surgery patients. At 6 and 12 months, it provided stable visual acuity across distance, intermediate, and near ranges, with minimal spherical equivalent refractive error. At the 0.2 logMAR level, the lens showed a continuous depth of field greater than 3.0D at 6 months. The four-haptic platform confirmed excellent rotational stability and centration, making it suitable for a toric version. Patients reported significant improvements in quality of life, especially in daily tasks. These findings suggest LuxLife is an effective solution for full-range vision