Comparison Of Surgical Outcomes Between Artisan And Carlevale/Soleko Intraocular Lens Implantation In Aphakic Patients: A Systematic Review And Meta-Analysis.
Published 2025 - 43rd Congress of the ESCRS
Reference: FP28.11 | Type: Free paper | DOI: 10.82333/t8e6-ez09
Authors: Arianna Serraiotto* 1 , Erika Bonacci 1 , Camilla Pagnacco 2 , Francesca Barzaghi 2 , Diletta Micochero 1 , Luca Polinelli 1 , Ettore Biondan 2 , Giorgio Marchini 2 , Emilio Pedrotti 1
1Department of Engineering for Innovation Medicine,University of Verona, Verona, Italy,Verona,Italy, 2Ophthalmology Clinic, Department of Surgery, Dentistry, Maternity and Infant,University of Verona, Verona, Italy,Verona,Italy
Purpose
To compare the surgical outcomes of the Artisan intraocular lens (IOL) with the Carlevale/Soleko IOL in terms of best-corrected visual acuity (BCVA) after surgery, surgical time, deviation from target refraction (SIA), and the most common complications through a systematic review (SR) and meta-analysis (MTA).
Setting
The study was conducted at the Ophthalmology Department of the General University Hospital of Elche.
Methods
A bibliographic search was conducted in PubMed, Cochrane, SciELO, and Scopus, along with a snowball search strategy, yielding six articles for the SR and MA. The articles were independently reviewed by two authors and assessed using the ROBINS-I tool. Statistical analysis was performed using the R programming language and the metafor package. A logarithmic risk ratio was calculated for discrete variables, while a standardized mean difference (MD) was used for continuous variables. If study heterogeneity was significant, a random-effects model was applied. Conversely, when heterogeneity was low, a fixed-effects model was used.
Results
Six articles were analyzed with a combined sample size of 479 eyes for Artisan group and 330 for Carlevale. The mean age for Artisan was 70.62 [68.33, 72.92] and 70.19 [68.76, 71.62] for Carlevale. The mean postoperative BCVA was 0.37 [0.31, 0.42] logMAR for Artisan and 0.36 [0.29, 0.42] for Carlevale, MD 0.01 [-0.08, 0.09]. The mean SIA for Artisan was 1.35 [0.83, 1.87] and 0.65 [0.39, 0.91] for Carlevale, with an MD of 0.69 [0.15, 1.23]. The mean surgical time was 53.24 [37.35, 69.13] min for Artisan and 56.34 [44.42, 68.27] for Carlevale. When comparing Artisan to Carlevale, the MD was 0.90 [0.48, 1.68] for corneal edema, 1.12 [0.83, 1.51] for macular edema, 0.13 [0.04, 0.47] for haptic extrusion, and 8.22 [1.95, 34.73] for dislocation.
Conclusions
The systematic review and meta-analysis demonstrate similar outcomes for both lenses in terms of postoperative BCVA, refractive deviation, induced astigmatism, and surgical time. This suggests that the choice should be left to the surgeon based on their expertise and the specific surgical case. Further clinical trials are needed to compare the results of both lenses in more depth.