Relationship Between Osdi Score And Subbasal Nerve Plexus Regeneration After 3 Myopia Correction Methods
Published 2025 - 43rd Congress of the ESCRS
Reference: FP26.14 | Type: Free paper | DOI: 10.82333/m9px-7045
Authors: Amber Ahmad Khattak 1 , Mohammed Muhtaseb* 2
1iLase Private clinic,Cardiff,United Kingdom, 2Ophthalmology,NHS,Cardiff,United Kingdom;Ophthalmology,University of Sulaimani Medical College,Sulimaniyah,Iraq;Ophthalmology,Hebron University Medical College,HebronHe,Palestinian, State of
Purpose
To evaluate the correlation between corneal sub-basal nerve plexus regeneration and OSDI score with corneal surface staining after 3 different keratorefractive procedures.
Setting
Refractive Surgery Department, Eye Hospital Svjetlost in Zagreb, Croatia
Methods
A prospective randomized study was conducted on 180 eyes evenly distributed in 3 groups according to surgical correction methods: TransepithelialPRK (SmartSURFACE), FS. LASIK and KLEX (SmartSIGHT) using Schwind ATOS for flap and lenticule formation and Schwind AMARIS 1050S for excimer laser ablation. Regeneration of corneal sub-basal nerve plexus was observed by IVCM, where nerve fiber lenght (CNFL) and nerve branch density (CNFD) was monitored. OSDI score along with corneal surface staining grade (Oxford grading scale) was measured at 1,3 and 6 months postoperativelly.
Results
Sub-basal nerve fiber density recovered faster in KLeX group conpared to Fs.LASIK group at 1 and 3 months, but no statistical difference was found at 6 months between two procedures. Sub-basal nerve density in the pedicle of corneal flap was higher than the other regions
Conclusions
All 3 surgical methods induced different degrees of dry eyes at first 3 months, with gradual recovery at 6-month period postoperatively.